Abstract
Seventy-six CEPH YACs were mapped by fluorescence in situ hybridization (FISH) to human metaphase chromosomes. These clones have been ordered from pter to 46 cM by combining the results of FISH with sequence-tagged site content mapping using data from the public databases. This created a minimal tiling path containing at least 37 Mb of human genomic DNA from 0 to 46 cM on chromosome 6 that contains up to four gaps not greater than 200 kb. These data provide an integration of the FLpter physical map values with cytogenetic band localization and markers on the genetic and radiation hybrid maps. We also assessed YAC chimerism and placed three additional Whitehead contigs (WC952, WC799, WC436) within the integrated map.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 104-111 |
| Number of pages | 8 |
| Journal | Genomics |
| Volume | 36 |
| Issue number | 1 |
| DOIs | |
| State | Published - Aug 15 1996 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Genetics
Cite this
FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6. / Bray-Ward, P.; Bowlus, Christopher; Choi, J.; Paslier, D. Le; Weissenbach, J.; Gruen, J. R.
In: Genomics, Vol. 36, No. 1, 15.08.1996, p. 104-111.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6
AU - Bray-Ward, P.
AU - Bowlus, Christopher
AU - Choi, J.
AU - Paslier, D. Le
AU - Weissenbach, J.
AU - Gruen, J. R.
PY - 1996/8/15
Y1 - 1996/8/15
N2 - Seventy-six CEPH YACs were mapped by fluorescence in situ hybridization (FISH) to human metaphase chromosomes. These clones have been ordered from pter to 46 cM by combining the results of FISH with sequence-tagged site content mapping using data from the public databases. This created a minimal tiling path containing at least 37 Mb of human genomic DNA from 0 to 46 cM on chromosome 6 that contains up to four gaps not greater than 200 kb. These data provide an integration of the FLpter physical map values with cytogenetic band localization and markers on the genetic and radiation hybrid maps. We also assessed YAC chimerism and placed three additional Whitehead contigs (WC952, WC799, WC436) within the integrated map.
AB - Seventy-six CEPH YACs were mapped by fluorescence in situ hybridization (FISH) to human metaphase chromosomes. These clones have been ordered from pter to 46 cM by combining the results of FISH with sequence-tagged site content mapping using data from the public databases. This created a minimal tiling path containing at least 37 Mb of human genomic DNA from 0 to 46 cM on chromosome 6 that contains up to four gaps not greater than 200 kb. These data provide an integration of the FLpter physical map values with cytogenetic band localization and markers on the genetic and radiation hybrid maps. We also assessed YAC chimerism and placed three additional Whitehead contigs (WC952, WC799, WC436) within the integrated map.
UR - http://www.scopus.com/inward/record.url?scp=0030586916&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030586916&partnerID=8YFLogxK
U2 - 10.1006/geno.1996.0430
DO - 10.1006/geno.1996.0430
M3 - Article
C2 - 8812421
AN - SCOPUS:0030586916
VL - 36
SP - 104
EP - 111
JO - Genomics
JF - Genomics
SN - 0888-7543
IS - 1
ER -