FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6

P. Bray-Ward, Christopher Bowlus, J. Choi, D. Le Paslier, J. Weissenbach, J. R. Gruen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Seventy-six CEPH YACs were mapped by fluorescence in situ hybridization (FISH) to human metaphase chromosomes. These clones have been ordered from pter to 46 cM by combining the results of FISH with sequence-tagged site content mapping using data from the public databases. This created a minimal tiling path containing at least 37 Mb of human genomic DNA from 0 to 46 cM on chromosome 6 that contains up to four gaps not greater than 200 kb. These data provide an integration of the FLpter physical map values with cytogenetic band localization and markers on the genetic and radiation hybrid maps. We also assessed YAC chimerism and placed three additional Whitehead contigs (WC952, WC799, WC436) within the integrated map.

Original languageEnglish (US)
Pages (from-to)104-111
Number of pages8
JournalGenomics
Volume36
Issue number1
DOIs
StatePublished - Aug 15 1996
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 6
Human Chromosomes
Fluorescence In Situ Hybridization
Sequence Tagged Sites
Radiation Hybrid Mapping
Chimerism
Metaphase
Genetic Markers
Cytogenetics
Clone Cells
Databases
DNA

ASJC Scopus subject areas

  • Genetics

Cite this

Bray-Ward, P., Bowlus, C., Choi, J., Paslier, D. L., Weissenbach, J., & Gruen, J. R. (1996). FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6. Genomics, 36(1), 104-111. https://doi.org/10.1006/geno.1996.0430

FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6. / Bray-Ward, P.; Bowlus, Christopher; Choi, J.; Paslier, D. Le; Weissenbach, J.; Gruen, J. R.

In: Genomics, Vol. 36, No. 1, 15.08.1996, p. 104-111.

Research output: Contribution to journalArticle

Bray-Ward, P, Bowlus, C, Choi, J, Paslier, DL, Weissenbach, J & Gruen, JR 1996, 'FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6', Genomics, vol. 36, no. 1, pp. 104-111. https://doi.org/10.1006/geno.1996.0430
Bray-Ward P, Bowlus C, Choi J, Paslier DL, Weissenbach J, Gruen JR. FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6. Genomics. 1996 Aug 15;36(1):104-111. https://doi.org/10.1006/geno.1996.0430
Bray-Ward, P. ; Bowlus, Christopher ; Choi, J. ; Paslier, D. Le ; Weissenbach, J. ; Gruen, J. R. / FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6. In: Genomics. 1996 ; Vol. 36, No. 1. pp. 104-111.
@article{19fa740d2c5045228dd258e5074638b1,
title = "FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6",
abstract = "Seventy-six CEPH YACs were mapped by fluorescence in situ hybridization (FISH) to human metaphase chromosomes. These clones have been ordered from pter to 46 cM by combining the results of FISH with sequence-tagged site content mapping using data from the public databases. This created a minimal tiling path containing at least 37 Mb of human genomic DNA from 0 to 46 cM on chromosome 6 that contains up to four gaps not greater than 200 kb. These data provide an integration of the FLpter physical map values with cytogenetic band localization and markers on the genetic and radiation hybrid maps. We also assessed YAC chimerism and placed three additional Whitehead contigs (WC952, WC799, WC436) within the integrated map.",
author = "P. Bray-Ward and Christopher Bowlus and J. Choi and Paslier, {D. Le} and J. Weissenbach and Gruen, {J. R.}",
year = "1996",
month = "8",
day = "15",
doi = "10.1006/geno.1996.0430",
language = "English (US)",
volume = "36",
pages = "104--111",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - FISH-mapped CEPH YACs spanning 0 to 46 cM on human chromosome 6

AU - Bray-Ward, P.

AU - Bowlus, Christopher

AU - Choi, J.

AU - Paslier, D. Le

AU - Weissenbach, J.

AU - Gruen, J. R.

PY - 1996/8/15

Y1 - 1996/8/15

N2 - Seventy-six CEPH YACs were mapped by fluorescence in situ hybridization (FISH) to human metaphase chromosomes. These clones have been ordered from pter to 46 cM by combining the results of FISH with sequence-tagged site content mapping using data from the public databases. This created a minimal tiling path containing at least 37 Mb of human genomic DNA from 0 to 46 cM on chromosome 6 that contains up to four gaps not greater than 200 kb. These data provide an integration of the FLpter physical map values with cytogenetic band localization and markers on the genetic and radiation hybrid maps. We also assessed YAC chimerism and placed three additional Whitehead contigs (WC952, WC799, WC436) within the integrated map.

AB - Seventy-six CEPH YACs were mapped by fluorescence in situ hybridization (FISH) to human metaphase chromosomes. These clones have been ordered from pter to 46 cM by combining the results of FISH with sequence-tagged site content mapping using data from the public databases. This created a minimal tiling path containing at least 37 Mb of human genomic DNA from 0 to 46 cM on chromosome 6 that contains up to four gaps not greater than 200 kb. These data provide an integration of the FLpter physical map values with cytogenetic band localization and markers on the genetic and radiation hybrid maps. We also assessed YAC chimerism and placed three additional Whitehead contigs (WC952, WC799, WC436) within the integrated map.

UR - http://www.scopus.com/inward/record.url?scp=0030586916&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030586916&partnerID=8YFLogxK

U2 - 10.1006/geno.1996.0430

DO - 10.1006/geno.1996.0430

M3 - Article

C2 - 8812421

AN - SCOPUS:0030586916

VL - 36

SP - 104

EP - 111

JO - Genomics

JF - Genomics

SN - 0888-7543

IS - 1

ER -