Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274 → Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+

Stefan Leitgeb, Barbara Petschacher, David K. Wilson, Bernd Nidetzky

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Medicine & Life Sciences