Fibrocartilaginous Embolism - An Uncommon Cause of Spinal Cord Infarction: A Case Report and Review of the Literature

Jay J. Han, Teresa L. Massagli, Kenneth M. Jaffe

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


Fibrocartilaginous embolism is a rare cause of spinal cord infarction. It is postulated that an acute vertical disk herniation of the nucleus pulposus material can lead to spinal cord infarction by a retrograde embolization to the central artery. An increased intradiskal pressure resulting from axial loading of the vertebral column with a concomitant Valsalva maneuver is thought to be the initiating event for the embolus. We present a previously healthy 16-year-old boy with sudden onset of back pain and progressive paraparesis within 36 hours after lifting exercises in a squat position. His clinical presentation and neuroimaging studies were consistent with spinal cord infarction resulting from a central artery embolus at the T8 spinal cord level. Laboratory investigation showed no evidence of infectious, autoimmune, inflammatory, or neoplastic causes. Although no histologic confirmation was obtained, lack of evidence for other plausible diagnoses in the setting of his clinical presentation and in the magnetic resonance imaging findings made fibrocartilaginous embolism myelopathy the most likely diagnosis. We postulated that some cases of transverse myelitis might actually be fibrocartilaginous embolism, making it a more prevalent cause of an acute myelopathy than commonly recognized. Relevant literature and current theories regarding the pathogenesis of fibrocartilaginous embolism myelopathy are reviewed.

Original languageEnglish (US)
Pages (from-to)153-157
Number of pages5
JournalArchives of Physical Medicine and Rehabilitation
Issue number1
StatePublished - Jan 2004
Externally publishedYes


  • Case report
  • Embolism
  • Fibrocartilage
  • Myelopathy
  • Rehabilitation
  • Spinal cord injuries

ASJC Scopus subject areas

  • Rehabilitation


Dive into the research topics of 'Fibrocartilaginous Embolism - An Uncommon Cause of Spinal Cord Infarction: A Case Report and Review of the Literature'. Together they form a unique fingerprint.

Cite this