Fetus in fetu in a harbor seal (Phoca vitulina richardi): Histopathologic, genetic, and toxicologic analysis

E. L. Buckles, F. M D Gulland, B. M. Aldridge, T. S. Gelatt, P. S. Ross, M. Haulena, Linda J Lowenstine

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A young harbor seal (Phoca vitulina richardi), stranded on the coast of California, was found to have a 20-cm-diameter cranial cervical mass. Surgical excision revealed the subcutaneous mass to be covered in haired skin with multiple glabrous areas and structures resembling a jaw with tooth buds, eyelids, and a tail. The mass deformed the host pup's skull. Histologic examination revealed a complete vertebra in the tail, teeth in the jaw, and areas resembling tongue and larynx. Class 1 MHC sequences amplified by polymerase chain reaction from the mass and the host twin were identical. The mass was diagnosed as a fetus in fetu, a rare congenital anomaly in which 1 conjoined twin is completely enclosed in the body of the other twin. The host pup died, and no additional defects were found; however, blubber levels of persistent organic pollutants were high. The cause of the congenital anomaly in this pup is uncertain.

Original languageEnglish (US)
Pages (from-to)541-544
Number of pages4
JournalVeterinary Pathology
Volume43
Issue number4
DOIs
StatePublished - 2006

Keywords

  • Congenital defect
  • Contaminants
  • Fetus in fetu
  • Harbor seal
  • Major histocompatibility complex
  • Phoca vitulina richardi
  • Twin

ASJC Scopus subject areas

  • veterinary(all)

Fingerprint Dive into the research topics of 'Fetus in fetu in a harbor seal (Phoca vitulina richardi): Histopathologic, genetic, and toxicologic analysis'. Together they form a unique fingerprint.

  • Cite this