Fetoscopic treatment for discordant twins

R. M. Sydorak, V. Feldstein, G. Machin, K. Tsao, Shinjiro Hirose, H. Lee, Diana L Farmer, M. R. Harrison, Craig T. Albanese

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Background/Purpose: In rare instances in monochorionic twin pregnancies, one twin can have a discordant anomaly (eg, cystic hygroma). If this twin dies in utero, neurologic injury and death can occur in the surviving cotwin. To protect the normal twin, the authors developed an approach to separate the circulations and ablate the umbilical cord of the abnormal twin. Methods: From September 1998 to February 2001, 6 cases of discordant anomalous twins were diagnosed by prenatal ultrasound scan in which the anomaly was lethal or parents desired prenatal termination for this abnormal twin. All underwent surgical intervention with gestational ages varying from 19 to 24 weeks. Results: Depending on cord insertion site and placental anatomy, blood flow was interrupted to the anomalous fetus by either radiofrequency ablation (RFA; 2 cases), cord transection (1 case), or cord transection after laser ablation of communicating vessels (3 cases). Fetal death occurred in one normal twin 4 days postoperatively. Average age at delivery for the 5 surviving fetuses was 34.5 weeks' gestation. On follow-up, all surviving infants are neurologically intact. Conclusion: An otherwise normal monochorionic twin threatened by an anomalous cotwin can be salvaged successfully with a strategy tailored to interrupt the vascular connections between the 2 twins.

Original languageEnglish (US)
Pages (from-to)1736-1739
Number of pages4
JournalJournal of Pediatric Surgery
Volume37
Issue number12
DOIs
StatePublished - Dec 1 2002

Fingerprint

Therapeutics
Fetus
Cystic Lymphangioma
Nervous System Trauma
Twin Pregnancy
Fetal Death
Umbilical Cord
Laser Therapy
Gestational Age
Blood Vessels
Anatomy
Parents
Pregnancy

Keywords

  • Discordant anomaly
  • Fetal surgery
  • Fetoscopy
  • Twins
  • Umbilical cord division

ASJC Scopus subject areas

  • Surgery

Cite this

Sydorak, R. M., Feldstein, V., Machin, G., Tsao, K., Hirose, S., Lee, H., ... Albanese, C. T. (2002). Fetoscopic treatment for discordant twins. Journal of Pediatric Surgery, 37(12), 1736-1739. https://doi.org/10.1053/jpsu.2002.36709

Fetoscopic treatment for discordant twins. / Sydorak, R. M.; Feldstein, V.; Machin, G.; Tsao, K.; Hirose, Shinjiro; Lee, H.; Farmer, Diana L; Harrison, M. R.; Albanese, Craig T.

In: Journal of Pediatric Surgery, Vol. 37, No. 12, 01.12.2002, p. 1736-1739.

Research output: Contribution to journalArticle

Sydorak, RM, Feldstein, V, Machin, G, Tsao, K, Hirose, S, Lee, H, Farmer, DL, Harrison, MR & Albanese, CT 2002, 'Fetoscopic treatment for discordant twins', Journal of Pediatric Surgery, vol. 37, no. 12, pp. 1736-1739. https://doi.org/10.1053/jpsu.2002.36709
Sydorak RM, Feldstein V, Machin G, Tsao K, Hirose S, Lee H et al. Fetoscopic treatment for discordant twins. Journal of Pediatric Surgery. 2002 Dec 1;37(12):1736-1739. https://doi.org/10.1053/jpsu.2002.36709
Sydorak, R. M. ; Feldstein, V. ; Machin, G. ; Tsao, K. ; Hirose, Shinjiro ; Lee, H. ; Farmer, Diana L ; Harrison, M. R. ; Albanese, Craig T. / Fetoscopic treatment for discordant twins. In: Journal of Pediatric Surgery. 2002 ; Vol. 37, No. 12. pp. 1736-1739.
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