Fetoscopic temporary tracheal occlusion by means of detachable balloon for congenital diaphragmatic hernia

Michael R. Harrison, Craig T. Albanese, Samuel B. Hawgood, Diana L Farmer, Jody A. Farrell, Per L. Sandberg, Roy A. Filly

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Occlusion of the fetal trachea blocks the egress of fetal lung fluid and stimulates the growth of hypoplastic lungs in fetuses with diaphragmatic hernia. Accomplishing temporary and reversible occlusion of the fetal trachea has proven difficult without invasive fetal surgery. Using simultaneous real-time ultrasonography and fetal bronchoscopy through a single uterine port, we placed a detachable balloon in the trachea of 2 fetuses with severe diaphragmatic hernia. In both fetuses the fetal lung subsequently enlarged, allowing survival after birth.

Original languageEnglish (US)
Pages (from-to)730-733
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Volume185
Issue number3
DOIs
StatePublished - 2001

Fingerprint

Trachea
Fetus
Diaphragmatic Hernia
Lung
Prenatal Ultrasonography
Bronchoscopy
Parturition
Growth
Congenital Diaphragmatic Hernias

Keywords

  • Congenital diaphragmatic hernia
  • Fetal surgery
  • Fetoscopy
  • Prenatal diagnosis
  • Tracheal occlusion

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Fetoscopic temporary tracheal occlusion by means of detachable balloon for congenital diaphragmatic hernia. / Harrison, Michael R.; Albanese, Craig T.; Hawgood, Samuel B.; Farmer, Diana L; Farrell, Jody A.; Sandberg, Per L.; Filly, Roy A.

In: American Journal of Obstetrics and Gynecology, Vol. 185, No. 3, 2001, p. 730-733.

Research output: Contribution to journalArticle

Harrison, Michael R. ; Albanese, Craig T. ; Hawgood, Samuel B. ; Farmer, Diana L ; Farrell, Jody A. ; Sandberg, Per L. ; Filly, Roy A. / Fetoscopic temporary tracheal occlusion by means of detachable balloon for congenital diaphragmatic hernia. In: American Journal of Obstetrics and Gynecology. 2001 ; Vol. 185, No. 3. pp. 730-733.
@article{b6e4bf91635246bfb67ed9b463bcc5c6,
title = "Fetoscopic temporary tracheal occlusion by means of detachable balloon for congenital diaphragmatic hernia",
abstract = "Occlusion of the fetal trachea blocks the egress of fetal lung fluid and stimulates the growth of hypoplastic lungs in fetuses with diaphragmatic hernia. Accomplishing temporary and reversible occlusion of the fetal trachea has proven difficult without invasive fetal surgery. Using simultaneous real-time ultrasonography and fetal bronchoscopy through a single uterine port, we placed a detachable balloon in the trachea of 2 fetuses with severe diaphragmatic hernia. In both fetuses the fetal lung subsequently enlarged, allowing survival after birth.",
keywords = "Congenital diaphragmatic hernia, Fetal surgery, Fetoscopy, Prenatal diagnosis, Tracheal occlusion",
author = "Harrison, {Michael R.} and Albanese, {Craig T.} and Hawgood, {Samuel B.} and Farmer, {Diana L} and Farrell, {Jody A.} and Sandberg, {Per L.} and Filly, {Roy A.}",
year = "2001",
doi = "10.1067/mob.2001.117344",
language = "English (US)",
volume = "185",
pages = "730--733",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "3",

}

TY - JOUR

T1 - Fetoscopic temporary tracheal occlusion by means of detachable balloon for congenital diaphragmatic hernia

AU - Harrison, Michael R.

AU - Albanese, Craig T.

AU - Hawgood, Samuel B.

AU - Farmer, Diana L

AU - Farrell, Jody A.

AU - Sandberg, Per L.

AU - Filly, Roy A.

PY - 2001

Y1 - 2001

N2 - Occlusion of the fetal trachea blocks the egress of fetal lung fluid and stimulates the growth of hypoplastic lungs in fetuses with diaphragmatic hernia. Accomplishing temporary and reversible occlusion of the fetal trachea has proven difficult without invasive fetal surgery. Using simultaneous real-time ultrasonography and fetal bronchoscopy through a single uterine port, we placed a detachable balloon in the trachea of 2 fetuses with severe diaphragmatic hernia. In both fetuses the fetal lung subsequently enlarged, allowing survival after birth.

AB - Occlusion of the fetal trachea blocks the egress of fetal lung fluid and stimulates the growth of hypoplastic lungs in fetuses with diaphragmatic hernia. Accomplishing temporary and reversible occlusion of the fetal trachea has proven difficult without invasive fetal surgery. Using simultaneous real-time ultrasonography and fetal bronchoscopy through a single uterine port, we placed a detachable balloon in the trachea of 2 fetuses with severe diaphragmatic hernia. In both fetuses the fetal lung subsequently enlarged, allowing survival after birth.

KW - Congenital diaphragmatic hernia

KW - Fetal surgery

KW - Fetoscopy

KW - Prenatal diagnosis

KW - Tracheal occlusion

UR - http://www.scopus.com/inward/record.url?scp=0034832447&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034832447&partnerID=8YFLogxK

U2 - 10.1067/mob.2001.117344

DO - 10.1067/mob.2001.117344

M3 - Article

C2 - 11568805

AN - SCOPUS:0034832447

VL - 185

SP - 730

EP - 733

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 3

ER -