Fetal Surgery for Myelomeningocele

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Myelomeningocele (MMC) is a congenital neural tube defect that occurs in approximately 1 in 2900 live births in the United States. It is a devastating disability with significant morbidity and mortality within the first few decades of life. MMC was the first nonlethal disease to be considered and studied for fetal surgery and is now the most common open fetal surgery performed. The recently completed MOMS randomized controlled trial has shown that fetal repair for MMC can improve hydrocephalus and hindbrain herniation, can reduce the need for vetriculoperitoneal shunting, and may improve distal neurologic function in some patients.

Original languageEnglish (US)
Pages (from-to)279-288
Number of pages10
JournalClinics in Perinatology
Volume39
Issue number2
DOIs
StatePublished - Jun 2012

Fingerprint

Meningomyelocele
Rhombencephalon
Neural Tube Defects
Live Birth
Hydrocephalus
Nervous System
Randomized Controlled Trials
Morbidity
Mortality

Keywords

  • Fetal surgery
  • Hydrocephalus
  • Myelomeningocele
  • Neural tube defect
  • Shunt
  • Spina bifida
  • Ventriculomegaly

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Fetal Surgery for Myelomeningocele. / Saadai, Payam; Farmer, Diana L.

In: Clinics in Perinatology, Vol. 39, No. 2, 06.2012, p. 279-288.

Research output: Contribution to journalArticle

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