Fetal neurosurgery: Current state of the art

Payam Saadai, Timothy Runyon, Diana L Farmer

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Congenital CNS abnormalities have been targets for prenatal intervention since the founding of fetal surgery 30 years ago, but with historically variable results. Open fetal neurosurgery for myelomenigocele has demonstrated the most promising results of any CNS malformation. Improvements in the understanding of congenital diseases and in fetal surgical techniques have reopened the door to applying fetal surgery to other congenital CNS abnormalities. Advances in gene therapy, bioengineering and neonatal neuroprotection will aid in the future expansion of fetal neurosurgery to other CNS disorders.

Original languageEnglish (US)
Pages (from-to)165-171
Number of pages7
JournalFuture Neurology
Volume6
Issue number2
DOIs
StatePublished - Mar 2011

Keywords

  • congenital neurodegenerative disorder
  • fetal neurosurgery
  • fetal surgery
  • gene therapy
  • hydrocephalus
  • myelomeningocele
  • spina bifida
  • stem cellstem cell

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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