Abstract
Background: Feline visceral hemangiosarcoma (HSA) is an uncommon tumor, and the clinical progression and outcome are rarely reported. Hypothesis: The prognosis of feline visceral HSA is poor because of severe clinical signs, anemia, and a high rate of metastasis. Animals: The medical records of 26 client-owned cats with visceral HSA were reviewed. Methods: Multi-institutional retrospective study. Results: The most common historical findings and clinical signs included lethargy, anorexia, respiratory difficulty, collapse, and vocalizing. Eighty-two percent of cats were anemic, and aspartate transaminase was increased in 53% of the study population. Metastatic lung disease was noted in 33% of affected cats. In 75% of the cats, abdominal ultrasonography identified a specific location of HSA. However, ultrasound identification of all multifocal lesions was successful only in 3/9 cats (33%). Tumor location was identified in the following organs: liver (35%), small intestine (31%), large intestine (31%), abdominal lymph node (31%), mesentery (27%), spleen (23%), lung (19%), omentum (12%), brain (8%), pancreas (8%), and diaphragm (8%). Multifocal HSA was noted in 77% of cats. Three cats received adjuvant chemotherapy (doxorubicin). Seventy-one percent of euthanized cats were euthanized within 1 day of diagnosis. The median survival time of the remaining cats (n = 6) was 77 days (range, 23-296 days). Conclusion and Clinical Importance: Feline visceral HSA is most often multifocal at the time of diagnosis. The prognosis appears poor, and the number of cats receiving chemotherapy is low.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 148-152 |
| Number of pages | 5 |
| Journal | Journal of Veterinary Internal Medicine |
| Volume | 22 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2008 |
| Externally published | Yes |
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Keywords
- Cat
- Malignant
- Neoplasia
ASJC Scopus subject areas
- veterinary(all)
Cite this
Feline visceral hemangiosarcoma. / Culp, William T; Drobatz, K. J.; Glassman, M. M.; Baez, J. L.; Aronson, L. R.
In: Journal of Veterinary Internal Medicine, Vol. 22, No. 1, 01.2008, p. 148-152.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Feline visceral hemangiosarcoma
AU - Culp, William T
AU - Drobatz, K. J.
AU - Glassman, M. M.
AU - Baez, J. L.
AU - Aronson, L. R.
PY - 2008/1
Y1 - 2008/1
N2 - Background: Feline visceral hemangiosarcoma (HSA) is an uncommon tumor, and the clinical progression and outcome are rarely reported. Hypothesis: The prognosis of feline visceral HSA is poor because of severe clinical signs, anemia, and a high rate of metastasis. Animals: The medical records of 26 client-owned cats with visceral HSA were reviewed. Methods: Multi-institutional retrospective study. Results: The most common historical findings and clinical signs included lethargy, anorexia, respiratory difficulty, collapse, and vocalizing. Eighty-two percent of cats were anemic, and aspartate transaminase was increased in 53% of the study population. Metastatic lung disease was noted in 33% of affected cats. In 75% of the cats, abdominal ultrasonography identified a specific location of HSA. However, ultrasound identification of all multifocal lesions was successful only in 3/9 cats (33%). Tumor location was identified in the following organs: liver (35%), small intestine (31%), large intestine (31%), abdominal lymph node (31%), mesentery (27%), spleen (23%), lung (19%), omentum (12%), brain (8%), pancreas (8%), and diaphragm (8%). Multifocal HSA was noted in 77% of cats. Three cats received adjuvant chemotherapy (doxorubicin). Seventy-one percent of euthanized cats were euthanized within 1 day of diagnosis. The median survival time of the remaining cats (n = 6) was 77 days (range, 23-296 days). Conclusion and Clinical Importance: Feline visceral HSA is most often multifocal at the time of diagnosis. The prognosis appears poor, and the number of cats receiving chemotherapy is low.
AB - Background: Feline visceral hemangiosarcoma (HSA) is an uncommon tumor, and the clinical progression and outcome are rarely reported. Hypothesis: The prognosis of feline visceral HSA is poor because of severe clinical signs, anemia, and a high rate of metastasis. Animals: The medical records of 26 client-owned cats with visceral HSA were reviewed. Methods: Multi-institutional retrospective study. Results: The most common historical findings and clinical signs included lethargy, anorexia, respiratory difficulty, collapse, and vocalizing. Eighty-two percent of cats were anemic, and aspartate transaminase was increased in 53% of the study population. Metastatic lung disease was noted in 33% of affected cats. In 75% of the cats, abdominal ultrasonography identified a specific location of HSA. However, ultrasound identification of all multifocal lesions was successful only in 3/9 cats (33%). Tumor location was identified in the following organs: liver (35%), small intestine (31%), large intestine (31%), abdominal lymph node (31%), mesentery (27%), spleen (23%), lung (19%), omentum (12%), brain (8%), pancreas (8%), and diaphragm (8%). Multifocal HSA was noted in 77% of cats. Three cats received adjuvant chemotherapy (doxorubicin). Seventy-one percent of euthanized cats were euthanized within 1 day of diagnosis. The median survival time of the remaining cats (n = 6) was 77 days (range, 23-296 days). Conclusion and Clinical Importance: Feline visceral HSA is most often multifocal at the time of diagnosis. The prognosis appears poor, and the number of cats receiving chemotherapy is low.
KW - Cat
KW - Malignant
KW - Neoplasia
UR - http://www.scopus.com/inward/record.url?scp=40549129398&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40549129398&partnerID=8YFLogxK
U2 - 10.1111/j.1939-1676.2008.0022.x
DO - 10.1111/j.1939-1676.2008.0022.x
M3 - Article
VL - 22
SP - 148
EP - 152
JO - Journal of Veterinary Internal Medicine
JF - Journal of Veterinary Internal Medicine
SN - 0891-6640
IS - 1
ER -