Feline Intracranial Neoplasia

Retrospective Review of 160 Cases (1985-2001)

Mark T. Troxel, Charles H. Vite, Thomas J. Van Winkle, Alisa L. Newton, Deena Tiches, Betsy Dayrell-Hart, Amy Kapatkin, Frances S. Shofer, Sheldon A. Steinberg

Research output: Contribution to journalArticle

134 Citations (Scopus)

Abstract

The purpose of this study was to determine the frequency of different tumor types within a large cohort of cats with intracranial neoplasia and to attempt to correlate signalment, tumor size and location, and survival time for each tumor. Medical records of 160 cats with confirmed intracranial neoplasia evaluated between 1985 and 2001 were reviewed. Parameters evaluated included age, sex, breed, FeLV/FIV status, clinical signs, duration of signs, number of tumors, tumor location(s), imaging results, treatment, survival times, and histopathologic diagnosis. Most of the cats were older (11.3 ± 3.8 years). Primary tumors accounted for 70.6% of cases. Metastasis and direct extension of secondary tumors accounted for only 5.6 and 3.8% of cases, respectively. Twelve cats (7.5%) had 2 or more discrete tumors of the same type, whereas 16 cats (10.0%) had 2 different types of intracranial tumors. The most common tumor types were meningioma (n = 93, 58.1%), lymphoma (n = 23, 14.4%), pituitary tumors (n = 14, 8.8%), and gliomas (n = 12, 7.5%). The most common neurological signs were altered consciousness (n = 42, 26.2%), circling (n = 36, 22.5%), and seizures (n = 36, 22.5%). Cats without specific neurological signs were common (n = 34, 21.2%). The tumor was considered an incidental finding in 30 (18.8%) cats. In addition to expected relationships (eg, meninges and meningioma, pituitary and pituitary tumors), we found that lesion location was predictive of tumor type with diffuse cerebral or brainstem involvement predictive of lymphoma and third ventricle involvement predictive of meningioma.

Original languageEnglish (US)
Pages (from-to)850-859
Number of pages10
JournalJournal of Veterinary Internal Medicine
Volume17
Issue number6
DOIs
StatePublished - Nov 2003
Externally publishedYes

Fingerprint

Felidae
cats
neoplasms
Neoplasms
Cats
Meningioma
Pituitary Neoplasms
lymphoma
Lymphoma
Feline Leukemia Virus
Feline Immunodeficiency Virus
Meninges
Third Ventricle
Incidental Findings
meninges
Consciousness
consciousness
Glioma
brain stem
seizures

Keywords

  • Brain tumor
  • Cat
  • Diagnosis
  • Glioma
  • Lymphoma
  • Meningioma

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Troxel, M. T., Vite, C. H., Van Winkle, T. J., Newton, A. L., Tiches, D., Dayrell-Hart, B., ... Steinberg, S. A. (2003). Feline Intracranial Neoplasia: Retrospective Review of 160 Cases (1985-2001). Journal of Veterinary Internal Medicine, 17(6), 850-859. https://doi.org/10.1892/0891-6640(2003)017<0850:FINRRO>2.3.CO;2

Feline Intracranial Neoplasia : Retrospective Review of 160 Cases (1985-2001). / Troxel, Mark T.; Vite, Charles H.; Van Winkle, Thomas J.; Newton, Alisa L.; Tiches, Deena; Dayrell-Hart, Betsy; Kapatkin, Amy; Shofer, Frances S.; Steinberg, Sheldon A.

In: Journal of Veterinary Internal Medicine, Vol. 17, No. 6, 11.2003, p. 850-859.

Research output: Contribution to journalArticle

Troxel, MT, Vite, CH, Van Winkle, TJ, Newton, AL, Tiches, D, Dayrell-Hart, B, Kapatkin, A, Shofer, FS & Steinberg, SA 2003, 'Feline Intracranial Neoplasia: Retrospective Review of 160 Cases (1985-2001)', Journal of Veterinary Internal Medicine, vol. 17, no. 6, pp. 850-859. https://doi.org/10.1892/0891-6640(2003)017<0850:FINRRO>2.3.CO;2
Troxel, Mark T. ; Vite, Charles H. ; Van Winkle, Thomas J. ; Newton, Alisa L. ; Tiches, Deena ; Dayrell-Hart, Betsy ; Kapatkin, Amy ; Shofer, Frances S. ; Steinberg, Sheldon A. / Feline Intracranial Neoplasia : Retrospective Review of 160 Cases (1985-2001). In: Journal of Veterinary Internal Medicine. 2003 ; Vol. 17, No. 6. pp. 850-859.
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abstract = "The purpose of this study was to determine the frequency of different tumor types within a large cohort of cats with intracranial neoplasia and to attempt to correlate signalment, tumor size and location, and survival time for each tumor. Medical records of 160 cats with confirmed intracranial neoplasia evaluated between 1985 and 2001 were reviewed. Parameters evaluated included age, sex, breed, FeLV/FIV status, clinical signs, duration of signs, number of tumors, tumor location(s), imaging results, treatment, survival times, and histopathologic diagnosis. Most of the cats were older (11.3 ± 3.8 years). Primary tumors accounted for 70.6{\%} of cases. Metastasis and direct extension of secondary tumors accounted for only 5.6 and 3.8{\%} of cases, respectively. Twelve cats (7.5{\%}) had 2 or more discrete tumors of the same type, whereas 16 cats (10.0{\%}) had 2 different types of intracranial tumors. The most common tumor types were meningioma (n = 93, 58.1{\%}), lymphoma (n = 23, 14.4{\%}), pituitary tumors (n = 14, 8.8{\%}), and gliomas (n = 12, 7.5{\%}). The most common neurological signs were altered consciousness (n = 42, 26.2{\%}), circling (n = 36, 22.5{\%}), and seizures (n = 36, 22.5{\%}). Cats without specific neurological signs were common (n = 34, 21.2{\%}). The tumor was considered an incidental finding in 30 (18.8{\%}) cats. In addition to expected relationships (eg, meninges and meningioma, pituitary and pituitary tumors), we found that lesion location was predictive of tumor type with diffuse cerebral or brainstem involvement predictive of lymphoma and third ventricle involvement predictive of meningioma.",
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