Feline infectious peritonitis in a mountain lion (Puma concolor), California, USA

Nicole Stephenson, Pamela Swift, Robert B. Moeller, S. Joy Worth, Janet E Foley

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Feline infectious peritonitis (FIP) is a fatal immune-mediated vasculitis of felids caused by a mutant form of a common feline enteric virus, feline enteric coronavirus. The virus can attack many organ systems and causes a broad range of signs, commonly including weight loss and fever. Regardless of presenta-tion, FIP is ultimately fatal and often presents a diagnostic challenge. In May 2010, a malnour-ished young adult male mountain lion (Puma concolor) from Kern County, California, USA was euthanized because of concern for public safety, and a postmortem examination was performed. Gross necropsy and histopathologic examination revealed necrotizing, multifocal myocarditis; necrotizing, neutrophilic, and his-tiocytic myositis and vasculitis of the tunica muscularis layer of the small and large intes-tines; and embolic, multifocal, interstitial pneu-monia. Feline coronavirus antigen was detect-ed in both the heart and intestinal tissue by immunohistochemistry. A PCR for coronavirus performed on kidney tissue was positive, con-firming a diagnosis of FIP. Although coronavirus infection has been documented in mountain lions by serology, this is the first confirmed report of FIP.

Original languageEnglish (US)
Pages (from-to)408-412
Number of pages5
JournalJournal of Wildlife Diseases
Volume49
Issue number2
DOIs
StatePublished - Apr 1 2013

Keywords

  • FeCV
  • Feline coronavirus
  • FIP
  • Immunohistochemistry
  • Mountain lion

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology

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