The 8p12 myeloproliferative syndrome is a distinct myeloid disorder associated with a translocation involving chromosome region 8p12 (HUGO nomenclature). It is characterized by leukocytosis, eosinophilia, and a concurrent or rapid transformation to a T-cell lymphoblastic lymphoma. We report a case of polycythemia vera as a clinical presentation of the 8p12 myeloproliferative syndrome and review the literature. Atypical features in patients with polycythemia vera should be investigated with cytogenetic evaluation.
|Original language||English (US)|
|Number of pages||3|
|Journal||Cancer Genetics and Cytogenetics|
|State||Published - May 2010|
ASJC Scopus subject areas
- Cancer Research
- Molecular Biology