Feasibility of vocal fold abduction and adduction assessment using cine-MRI

Marina Mat Baki, Alex Menys, David Atkinson, Paul Bassett, Simon Morley, Timothy Beale, Guri Sandhu, Georgekutty Naduvilethil, Nicola Stevenson, Martin A. Birchall, Shonit Punwani

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: Determine feasibility of vocal fold (VF) abduction and adduction assessment by cine magnetic resonance imaging (cine-MRI) Methods: Cine-MRI of the VF was performed on five healthy and nine unilateral VF paralysis (UVFP) participants using an axial gradient echo acquisition with temporal resolution of 0.7 s. VFs were continuously imaged with cine-MRI during a 10-s period of quiet respiration and phonation. Scanning was repeated twice within an individual session and then once again at a 1-week interval. Asymmetry of VF position during phonation (VF phonation asymmetry, VFPa) and respiration (VF respiration asymmetry, VFRa) was determined. Percentage reduction in total glottal area between respiration and phonation (VF abduction potential, VFAP) was derived to measure overall mobility. An un-paired t-test was used to compare differences between groups. Intra-session, inter-session and inter-reader repeatability of the quantitative metrics was evaluated using intraclass correlation coefficient (ICC). Results: VF position asymmetry (VFPa and VFRa) was greater (p=0.012; p=0.001) and overall mobility (VFAP) was lower (p=0.008) in UVFP patients compared with healthy participants. ICC of repeatability of all metrics was good, ranged from 0.82 to 0.95 except for the inter-session VFPa (0.44). Conclusion: Cine-MRI is feasible for assessing VF abduction and adduction. Derived quantitative metrics have good repeatability. Key points: • Cine-MRI is used to assess vocal folds (VFs) mobility: abduction and adduction.• New quantitative metrics are derived from VF position and abduction potential.• Cine-MRI able to depict the difference between normal and abnormal VF mobility.• Cine-MRI derived quantitative metrics have good repeatability.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalEuropean Radiology
DOIs
StateAccepted/In press - Apr 16 2016

Fingerprint

Cine Magnetic Resonance Imaging
Vocal Cords
Phonation
Respiration
Paralysis

Keywords

  • Cine
  • Feasibility study
  • Magnetic resonance imaging
  • Vocal fold paralysis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Baki, M. M., Menys, A., Atkinson, D., Bassett, P., Morley, S., Beale, T., ... Punwani, S. (Accepted/In press). Feasibility of vocal fold abduction and adduction assessment using cine-MRI. European Radiology, 1-9. https://doi.org/10.1007/s00330-016-4341-3

Feasibility of vocal fold abduction and adduction assessment using cine-MRI. / Baki, Marina Mat; Menys, Alex; Atkinson, David; Bassett, Paul; Morley, Simon; Beale, Timothy; Sandhu, Guri; Naduvilethil, Georgekutty; Stevenson, Nicola; Birchall, Martin A.; Punwani, Shonit.

In: European Radiology, 16.04.2016, p. 1-9.

Research output: Contribution to journalArticle

Baki, MM, Menys, A, Atkinson, D, Bassett, P, Morley, S, Beale, T, Sandhu, G, Naduvilethil, G, Stevenson, N, Birchall, MA & Punwani, S 2016, 'Feasibility of vocal fold abduction and adduction assessment using cine-MRI', European Radiology, pp. 1-9. https://doi.org/10.1007/s00330-016-4341-3
Baki, Marina Mat ; Menys, Alex ; Atkinson, David ; Bassett, Paul ; Morley, Simon ; Beale, Timothy ; Sandhu, Guri ; Naduvilethil, Georgekutty ; Stevenson, Nicola ; Birchall, Martin A. ; Punwani, Shonit. / Feasibility of vocal fold abduction and adduction assessment using cine-MRI. In: European Radiology. 2016 ; pp. 1-9.
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abstract = "Objective: Determine feasibility of vocal fold (VF) abduction and adduction assessment by cine magnetic resonance imaging (cine-MRI) Methods: Cine-MRI of the VF was performed on five healthy and nine unilateral VF paralysis (UVFP) participants using an axial gradient echo acquisition with temporal resolution of 0.7 s. VFs were continuously imaged with cine-MRI during a 10-s period of quiet respiration and phonation. Scanning was repeated twice within an individual session and then once again at a 1-week interval. Asymmetry of VF position during phonation (VF phonation asymmetry, VFPa) and respiration (VF respiration asymmetry, VFRa) was determined. Percentage reduction in total glottal area between respiration and phonation (VF abduction potential, VFAP) was derived to measure overall mobility. An un-paired t-test was used to compare differences between groups. Intra-session, inter-session and inter-reader repeatability of the quantitative metrics was evaluated using intraclass correlation coefficient (ICC). Results: VF position asymmetry (VFPa and VFRa) was greater (p=0.012; p=0.001) and overall mobility (VFAP) was lower (p=0.008) in UVFP patients compared with healthy participants. ICC of repeatability of all metrics was good, ranged from 0.82 to 0.95 except for the inter-session VFPa (0.44). Conclusion: Cine-MRI is feasible for assessing VF abduction and adduction. Derived quantitative metrics have good repeatability. Key points: • Cine-MRI is used to assess vocal folds (VFs) mobility: abduction and adduction.• New quantitative metrics are derived from VF position and abduction potential.• Cine-MRI able to depict the difference between normal and abnormal VF mobility.• Cine-MRI derived quantitative metrics have good repeatability.",
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AU - Bassett, Paul

AU - Morley, Simon

AU - Beale, Timothy

AU - Sandhu, Guri

AU - Naduvilethil, Georgekutty

AU - Stevenson, Nicola

AU - Birchall, Martin A.

AU - Punwani, Shonit

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AB - Objective: Determine feasibility of vocal fold (VF) abduction and adduction assessment by cine magnetic resonance imaging (cine-MRI) Methods: Cine-MRI of the VF was performed on five healthy and nine unilateral VF paralysis (UVFP) participants using an axial gradient echo acquisition with temporal resolution of 0.7 s. VFs were continuously imaged with cine-MRI during a 10-s period of quiet respiration and phonation. Scanning was repeated twice within an individual session and then once again at a 1-week interval. Asymmetry of VF position during phonation (VF phonation asymmetry, VFPa) and respiration (VF respiration asymmetry, VFRa) was determined. Percentage reduction in total glottal area between respiration and phonation (VF abduction potential, VFAP) was derived to measure overall mobility. An un-paired t-test was used to compare differences between groups. Intra-session, inter-session and inter-reader repeatability of the quantitative metrics was evaluated using intraclass correlation coefficient (ICC). Results: VF position asymmetry (VFPa and VFRa) was greater (p=0.012; p=0.001) and overall mobility (VFAP) was lower (p=0.008) in UVFP patients compared with healthy participants. ICC of repeatability of all metrics was good, ranged from 0.82 to 0.95 except for the inter-session VFPa (0.44). Conclusion: Cine-MRI is feasible for assessing VF abduction and adduction. Derived quantitative metrics have good repeatability. Key points: • Cine-MRI is used to assess vocal folds (VFs) mobility: abduction and adduction.• New quantitative metrics are derived from VF position and abduction potential.• Cine-MRI able to depict the difference between normal and abnormal VF mobility.• Cine-MRI derived quantitative metrics have good repeatability.

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