Fatal pneumonia following inoculation of healthy bighorn sheep with Pasteurella haemolytica from healthy domestic sheep.

W. J. Foreyt, K. P. Snipes, R. W. Kasten

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

In a series of three experiments, isolates of Pasteurella haemolytica biotype A, serotype 2, ribotype reference WSU-1, from healthy domestic sheep, were inoculated intratracheally into eight bighorn sheep (Ovis canadensis canadensis) and seven domestic sheep with doses of bacteria ranging from 5.3 x 10(8) to 8.6 x 10(11) colony forming units. Seven of eight inoculated bighorn sheep died from acute pneumonia within 48 hr of inoculation, whereas all seven domestic sheep inoculated with comparable or greater doses of bacteria remained healthy. One contact control bighorn sheep also died 6 days after its penmates received P. haemolytica. Three other noncontact control bighorn sheep remained healthy during the experiments. Pasteurella haemolytica biotype A, serotype 2, ribotype reference WSU-1 in the inocula was recovered from one or more tissues from all bighorns that died; whereas, it was not detected in any bighorn sheep before inoculation. Three different ribotypes of P. haemolytica A2 were recovered from bighorn sheep; however, only the ribotype reference WSU-1 in the domestic sheep-origin inoculum was recovered from all dead bighorn sheep, and was not recovered from bighorn sheep that survived the experiments. Thus, a relatively nonpathogenic and common isolate of P. haemolytica from healthy domestic sheep was lethal in bighorn sheep under experimental conditions.

Original languageEnglish (US)
Pages (from-to)137-145
Number of pages9
JournalJournal of Wildlife Diseases
Volume30
Issue number2
StatePublished - Apr 1994
Externally publishedYes

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Bighorn Sheep
Domestic Sheep
Mannheimia haemolytica
Ovis canadensis
pneumonia
sheep
inoculation
Pneumonia
Ribotyping
ribotypes
biotypes
biotype
inoculum
serotypes
Bacteria
bacteria
dosage
varespladib methyl
bacterium

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Fatal pneumonia following inoculation of healthy bighorn sheep with Pasteurella haemolytica from healthy domestic sheep. / Foreyt, W. J.; Snipes, K. P.; Kasten, R. W.

In: Journal of Wildlife Diseases, Vol. 30, No. 2, 04.1994, p. 137-145.

Research output: Contribution to journalArticle

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