Abstract
Although lymphocytic choriomeningitis virus usually produces a benign aseptic meningitis and rarely causes death, a fatal case of acute meningoencephalitis due to LCM occurred in a 19 year old girl. The principal histologic manifestations were lymphocytic and monocytic infiltrates in the meninges and Virchow-Robin spaces and focal inflammatory nodules in the pons and medulla. The virus was isolated from the patient’s brain and complement-fixing and neutralizing antibodies were detected in the serum. Immunofluorescence studies showed viral antigen in the meninges and in the cytoplasm of the cerebral neurons.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 198-203 |
| Number of pages | 6 |
| Journal | Neurology |
| Volume | 23 |
| Issue number | 2 |
| State | Published - Jan 1 1973 |
| Externally published | Yes |
ASJC Scopus subject areas
- Clinical Neurology
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Cite this
Warkel, R. L., Rinaldi, C. F., Bancroft, W. H., Cardiff, R., Holmes, G. E., & Wilsnack, R. E. (1973). Fatal acute meningoencephalitis due to lymphocytic choriomeningitis virus. Neurology, 23(2), 198-203.