Response to diet and drug therapy was assessed in a group of 85 Indian patients with non-insulin-dependent diabetes in the young (NIDDY). There was a significant decrease in fasting plasma glucose (FPG) values on therapy (pretreatment 13.3 ± 0.5 mmol/l; post-treatment 9.7 ± 0.4 mmol/l) (P<0.001). Prior to therapy the majority of patients had either moderate (40%) or severe (59%) diabetes; on therapy, the majority had either mild (21%) or moderate (62%) diabetes. Estimation of glycosylated haemoglobin (Hb A1) levels revealed that control was excellent (Hb A1<10%) in 47% of patients and excellent or adequate (Hb A1≤12%) in 78%. Hb A1 levels correlated significantly with the FPG value (r = 0.78; P<0.001). In 8 patients with iron deficiency anaemia the Hb A1 level did not fall within the correlation norms between Hb A1 and FPG. Treatment of the anaemia restored the correlative norms. Hb A1 levels were significantly higher in patients with microvascular complications (12.1 ± 0.8%) than in those without any vascular complications (10.3 ± 0.3%) (P<0.01).
|Original language||English (US)|
|Number of pages||3|
|Journal||South African Medical Journal|
|State||Published - 1982|
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