Fast, flexible algorithm for calculating photon correlations

Ted A. Laurence, Samantha Fore, Thomas R Huser

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

We introduce a new algorithm for computing correlations of photon arrival time data acquired in single-molecule fluorescence spectroscopy and fluorescence correlation spectroscopy (FCS). The algorithm is based on rewriting the correlation as a counting operation on photon pairs and can be used with arbitrary bin widths and spacing. The flexibility of the algorithm is demonstrated by use of FCS simulations and single-molecule photon antibunching experiments. Execution speed is comparable to the commonly used multiple-tau correlation technique. Wide bin spacings are possible that allow for real-time software calculation of correlations, even for high count rates.

Original languageEnglish (US)
Pages (from-to)829-831
Number of pages3
JournalOptics Letters
Volume31
Issue number6
DOIs
StatePublished - Mar 15 2006

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photons
fluorescence
spacing
spectroscopy
arrivals
molecules
counting
flexibility
computer programs
simulation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Fast, flexible algorithm for calculating photon correlations. / Laurence, Ted A.; Fore, Samantha; Huser, Thomas R.

In: Optics Letters, Vol. 31, No. 6, 15.03.2006, p. 829-831.

Research output: Contribution to journalArticle

Laurence, TA, Fore, S & Huser, TR 2006, 'Fast, flexible algorithm for calculating photon correlations', Optics Letters, vol. 31, no. 6, pp. 829-831. https://doi.org/10.1364/OL.31.000829
Laurence, Ted A. ; Fore, Samantha ; Huser, Thomas R. / Fast, flexible algorithm for calculating photon correlations. In: Optics Letters. 2006 ; Vol. 31, No. 6. pp. 829-831.
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