Abstract
Objective: To describe false increases in plasma lactate concentration measured on point-of-care analyzers in 2 dogs with ethylene glycol (EG) intoxication. Case Summary: Two dogs presenting with EG intoxication had extreme increases of plasma lactate concentrations recorded on a point-of-care machine. Laboratory analysis by spectrophotometry of lactate concentration determined these lactate measurements to be erroneous. False increases in plasma lactate concentration were demonstrated in 2 out of 3 point-of-care machines tested. New or Unique Information Provided: Glycolate, a toxic metabolite of EG, can interfere with the measurement of plasma lactate by some analyzers and this may delay the correct diagnosis of EG toxicity if not recognized.
Original language | English (US) |
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Pages (from-to) | 63-67 |
Number of pages | 5 |
Journal | Journal of Veterinary Emergency and Critical Care |
Volume | 23 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2013 |
Keywords
- Anti-freeze toxicity
- Glycolate
- Hyperlactatemia
- Lab error
ASJC Scopus subject areas
- veterinary(all)