False DNA aneuploidy in canine and human neoplasms

A. D. Deitch, Ralph W deVere White, B. R. Madewell

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

In most cases the appearance of aneuploid peaks in DNA histograms may be an artefact of tissue preparation or it may reflect non-stoichiometric dye binding of a cellular subpopulation rather than true DNA aneuploidy. This report reviews how false DNA aneuploidy can be recognized and eliminated from sample submitted for DNA flow cytometric analysis.

Original languageEnglish (US)
Pages (from-to)2117-2118
Number of pages2
JournalAnticancer Research
Volume13
Issue number6 A
StatePublished - 1993

Keywords

  • DNA neoplasms
  • Flow cytometry
  • Prostate neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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