Fall in antibody titer to bovine leukemia virus in the periparturient period

M. J. Burridge, Mark Thurmond, J. M. Miller, M. J. Schmerr, M. J. Van Der Maaten

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Twenty-seven cows with antibodies to bovine leukemia virus were bled before, during and after calving. All serum samples were tested quantitatively for bovine leukemia virus antibodies using both the agar-gel immunodiffusion test with a glycoprotein antigen and the radioimmunoprecipitation assay with an internal p24 protein antigen. A significant fall (P < 0.001) in bovine leukemia virus-antibody titer was demonstrated with both tests at the time of calving, with a subsequent rise in antibody titer within one month of parturition. Bovine leukemia virus antibodies were not detectable using the agar-gel immunodiffusion test in two of these cows at the time of calving.

Original languageEnglish (US)
Pages (from-to)270-271
Number of pages2
JournalCanadian Journal of Comparative Medicine
Issue number3
StatePublished - Dec 1 1982
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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