Failure to protect Mus musculus against Plasmodium berghei with footpad injections of killed parasites incorporated in complete Freund's adjuvant

William Reisen; T. C. Hillis

doi:10.2307/3279241

Failure to protect Mus musculus against Plasmodium berghei with footpad injections of killed parasites incorporated in complete Freund's adjuvant

William Reisen, T. C. Hillis

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The stimulation of cell mediated immunity by the injection of antigen from killed parasites incorporated in complete Freund's adjuvant did not protect Mus musculus from the erythrocytic stages of Plasmodium berghei. Agglutinating antibodies could not be detected, but delayed hypersensitivity was demonstrable. Apparently thymocyte sensitization alone was not sufficient to afford protection.

Original language	English (US)
Pages (from-to)	937-940
Number of pages	4
Journal	Journal of Parasitology
Volume	61
Issue number	5
DOIs	https://doi.org/10.2307/3279241
State	Published - Jan 1 1975
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Ecology, Evolution, Behavior and Systematics

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title = "Failure to protect Mus musculus against Plasmodium berghei with footpad injections of killed parasites incorporated in complete Freund's adjuvant",

abstract = "The stimulation of cell mediated immunity by the injection of antigen from killed parasites incorporated in complete Freund's adjuvant did not protect Mus musculus from the erythrocytic stages of Plasmodium berghei. Agglutinating antibodies could not be detected, but delayed hypersensitivity was demonstrable. Apparently thymocyte sensitization alone was not sufficient to afford protection.",

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