Failure to protect Mus musculus against Plasmodium berghei with footpad injections of killed parasites incorporated in complete Freund's adjuvant

William Reisen, T. C. Hillis

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The stimulation of cell mediated immunity by the injection of antigen from killed parasites incorporated in complete Freund's adjuvant did not protect Mus musculus from the erythrocytic stages of Plasmodium berghei. Agglutinating antibodies could not be detected, but delayed hypersensitivity was demonstrable. Apparently thymocyte sensitization alone was not sufficient to afford protection.

Original languageEnglish (US)
Pages (from-to)937-940
Number of pages4
JournalJournal of Parasitology
Volume61
Issue number5
DOIs
StatePublished - Jan 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Ecology, Evolution, Behavior and Systematics

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