Failure to identify an association between serologic or molecular evidence of Bartonella infection and idiopathic rhinitis in dogs

Eleanor C. Hawkins, Lynelle R Johnson, Lynn Guptill, Henry S. Marr, Edward B. Breitschwerdt, Adam J. Birkenheuer

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective - To determine whether infection with or exposure to Bartonella spp was associated with idiopathic rhinitis in dogs. Design - Case-control study. Animals - 44 dogs with idiopathic nasal discharge and 63 age- and weight-matched control dogs without nasal discharge and no clinical signs of bartonellosis. Procedures - Serum was tested for antibodies against Bartonella henselae and Bartonella vinsonii subsp berkhoffii with indirect fluorescent antibody assays. Blood was tested for Bartonella DNA with a PCR assay. Results - Results of the antibody and PCR assays were negative for all 44 dogs with idiopathic nasal discharge. One control dog had antibodies against B henselae; a second control dog had positive PCR assay results. We did not detect a significant association between assay results and group designation. Conclusions and Clinical Relevance - The present study failed to confirm an association between idiopathic rhinitis and exposure to or infection with Bartonella spp in dogs. Findings do not rule out the possibility that Bartonella infection may cause nasal discharge in some dogs, but the failure to find any evidence of exposure to or infection with Bartonella spp in dogs with idiopathic nasal discharge suggested that Bartonella infection was not a common cause of the disease.

Original languageEnglish (US)
Pages (from-to)597-599
Number of pages3
JournalJournal of the American Veterinary Medical Association
Volume233
Issue number4
DOIs
StatePublished - Aug 15 2008

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Bartonella Infections
Bartonella
rhinitis
Rhinitis
Dogs
dogs
Nose
infection
assays
antibodies
Antibodies
Polymerase Chain Reaction
Bartonella vinsonii
Bartonella henselae
weight control
blood serum
case-control studies
Case-Control Studies

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Failure to identify an association between serologic or molecular evidence of Bartonella infection and idiopathic rhinitis in dogs. / Hawkins, Eleanor C.; Johnson, Lynelle R; Guptill, Lynn; Marr, Henry S.; Breitschwerdt, Edward B.; Birkenheuer, Adam J.

In: Journal of the American Veterinary Medical Association, Vol. 233, No. 4, 15.08.2008, p. 597-599.

Research output: Contribution to journalArticle

Hawkins, Eleanor C. ; Johnson, Lynelle R ; Guptill, Lynn ; Marr, Henry S. ; Breitschwerdt, Edward B. ; Birkenheuer, Adam J. / Failure to identify an association between serologic or molecular evidence of Bartonella infection and idiopathic rhinitis in dogs. In: Journal of the American Veterinary Medical Association. 2008 ; Vol. 233, No. 4. pp. 597-599.
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