Failure to demonstrate a major anti-inflammatory effect with alpha tocopherol supplementation (400 IU/day) in normal subjects

Nalini Kaul; Sridevi Devaraj; Scott M. Grundy; Ishwarlal Jialal

doi:10.1016/S0002-9149(01)01534-X

Failure to demonstrate a major anti-inflammatory effect with alpha tocopherol supplementation (400 IU/day) in normal subjects

Nalini Kaul, Sridevi Devaraj, Scott M. Grundy, Ishwarlal Jialal

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

In summary, our data indicate that supplementation of healthy volunteers with 400 IU/day of AT has no effect on most markers of inflammation. Because significant effects have been seen with higher doses (1,200 IU/day), a dose-response study will prove very instructive.

Original language	English (US)
Pages (from-to)	1320-1323
Number of pages	4
Journal	American Journal of Cardiology
Volume	87
Issue number	11
DOIs	https://doi.org/10.1016/S0002-9149(01)01534-X
State	Published - Jun 1 2001
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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title = "Failure to demonstrate a major anti-inflammatory effect with alpha tocopherol supplementation (400 IU/day) in normal subjects",

abstract = "In summary, our data indicate that supplementation of healthy volunteers with 400 IU/day of AT has no effect on most markers of inflammation. Because significant effects have been seen with higher doses (1,200 IU/day), a dose-response study will prove very instructive.",

author = "Nalini Kaul and Sridevi Devaraj and Grundy, {Scott M.} and Ishwarlal Jialal",

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AU - Jialal, Ishwarlal

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AB - In summary, our data indicate that supplementation of healthy volunteers with 400 IU/day of AT has no effect on most markers of inflammation. Because significant effects have been seen with higher doses (1,200 IU/day), a dose-response study will prove very instructive.

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