Faecal virome of cats in an animal shelter

Wen Zhang, Linlin Li, Xutao Deng, Beatrix Kapusinszky, Patricia Pesavento, Eric Delwart

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

We describe the metagenomics-derived feline enteric virome in the faeces of 25 cats from a single shelter in California. More than 90% of the recognizable viral reads were related to mammalian viruses and the rest to bacterial viruses. Eight viral families were detected: Astroviridae, Coronaviridae, Parvoviridae, Circoviridae, Herpesviridae, Anelloviridae, Caliciviridae and Picobirnaviridae. Six previously known viruses were also identified: feline coronavirus type 1, felid herpes 1, feline calicivirus, feline norovirus, feline panleukopenia virus and picobirnavirus. Novel species of astroviruses and bocaviruses, and the first genome of a cyclovirus in a feline were characterized. The RNA-dependent RNA polymerase region from four highly divergent partial viral genomes in the order Picornavirales were sequenced. The detection of such a diverse collection of viruses shed within a single shelter suggested that such animals experience robust viral exposures. This study increases our understanding of the viral diversity in cats, facilitating future evaluation of their pathogenic and zoonotic potentials.

Original languageEnglish (US)
Pages (from-to)2553-2564
Number of pages12
JournalJournal of General Virology
Volume95
DOIs
StatePublished - Nov 1 2014

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Felidae
Cats
Viruses
Astroviridae
Anelloviridae
Picobirnavirus
Circoviridae
Coronaviridae
Parvoviridae
Caliciviridae
Feline Panleukopenia Virus
Bocavirus
Feline Coronavirus
Feline Calicivirus
RNA Replicase
Norovirus
Metagenomics
Viral Genome
Herpesviridae
Zoonoses

ASJC Scopus subject areas

  • Virology
  • Medicine(all)

Cite this

Zhang, W., Li, L., Deng, X., Kapusinszky, B., Pesavento, P., & Delwart, E. (2014). Faecal virome of cats in an animal shelter. Journal of General Virology, 95, 2553-2564. https://doi.org/10.1099/vir.0.069674-0

Faecal virome of cats in an animal shelter. / Zhang, Wen; Li, Linlin; Deng, Xutao; Kapusinszky, Beatrix; Pesavento, Patricia; Delwart, Eric.

In: Journal of General Virology, Vol. 95, 01.11.2014, p. 2553-2564.

Research output: Contribution to journalArticle

Zhang, W, Li, L, Deng, X, Kapusinszky, B, Pesavento, P & Delwart, E 2014, 'Faecal virome of cats in an animal shelter', Journal of General Virology, vol. 95, pp. 2553-2564. https://doi.org/10.1099/vir.0.069674-0
Zhang, Wen ; Li, Linlin ; Deng, Xutao ; Kapusinszky, Beatrix ; Pesavento, Patricia ; Delwart, Eric. / Faecal virome of cats in an animal shelter. In: Journal of General Virology. 2014 ; Vol. 95. pp. 2553-2564.
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