Fabrication of silicon-based nanoparticles for biological imaging

Xiaoming Zhang, Doinita Neiner, Shizhong Wang, Angelique Y. Louie, Susan M. Kauzlarich

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Fluorescent silicon nanomaterials have initiated great interest for their potential biological applications. In this paper, we report the synthesis of water-soluble, luminescent silicon nanoparticles with high quantum yield. The surfaces of the Si nanoparticles were capped by hydrophobic or hydrophilic organic molecules that passivate and protect the silicon particles from oxidation. The as-synthesized silicon nanoparticles displayed strong photoluminescence in the blue region of the visible spectrum. The attached organic molecules conveyed both water solubility and high stability, and coating had little adverse effect on the optical properties of nanoparticles. These results have major implications towards using colloidal silicon nanoparticles effectively in biological fluorescence imaging.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6448
DOIs
StatePublished - 2007
EventColloidal Quantum Dots for Biomedical Applications II - San Jose, CA, United States
Duration: Jan 20 2007Jan 23 2007

Other

OtherColloidal Quantum Dots for Biomedical Applications II
CountryUnited States
CitySan Jose, CA
Period1/20/071/23/07

Fingerprint

Nanoparticles
Imaging techniques
Fabrication
Silicon
Molecules
Quantum yield
Nanostructured materials
Water
Photoluminescence
Optical properties
Solubility
Fluorescence
Coatings
Oxidation

Keywords

  • Fluorescence imaging
  • Photo luminescence
  • Silicon
  • Water-soluble

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Zhang, X., Neiner, D., Wang, S., Louie, A. Y., & Kauzlarich, S. M. (2007). Fabrication of silicon-based nanoparticles for biological imaging. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6448). [644804] https://doi.org/10.1117/12.701442

Fabrication of silicon-based nanoparticles for biological imaging. / Zhang, Xiaoming; Neiner, Doinita; Wang, Shizhong; Louie, Angelique Y.; Kauzlarich, Susan M.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6448 2007. 644804.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zhang, X, Neiner, D, Wang, S, Louie, AY & Kauzlarich, SM 2007, Fabrication of silicon-based nanoparticles for biological imaging. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6448, 644804, Colloidal Quantum Dots for Biomedical Applications II, San Jose, CA, United States, 1/20/07. https://doi.org/10.1117/12.701442
Zhang X, Neiner D, Wang S, Louie AY, Kauzlarich SM. Fabrication of silicon-based nanoparticles for biological imaging. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6448. 2007. 644804 https://doi.org/10.1117/12.701442
Zhang, Xiaoming ; Neiner, Doinita ; Wang, Shizhong ; Louie, Angelique Y. ; Kauzlarich, Susan M. / Fabrication of silicon-based nanoparticles for biological imaging. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6448 2007.
@inproceedings{a050bdcca68e4fc8af137483d8f9c107,
title = "Fabrication of silicon-based nanoparticles for biological imaging",
abstract = "Fluorescent silicon nanomaterials have initiated great interest for their potential biological applications. In this paper, we report the synthesis of water-soluble, luminescent silicon nanoparticles with high quantum yield. The surfaces of the Si nanoparticles were capped by hydrophobic or hydrophilic organic molecules that passivate and protect the silicon particles from oxidation. The as-synthesized silicon nanoparticles displayed strong photoluminescence in the blue region of the visible spectrum. The attached organic molecules conveyed both water solubility and high stability, and coating had little adverse effect on the optical properties of nanoparticles. These results have major implications towards using colloidal silicon nanoparticles effectively in biological fluorescence imaging.",
keywords = "Fluorescence imaging, Photo luminescence, Silicon, Water-soluble",
author = "Xiaoming Zhang and Doinita Neiner and Shizhong Wang and Louie, {Angelique Y.} and Kauzlarich, {Susan M.}",
year = "2007",
doi = "10.1117/12.701442",
language = "English (US)",
isbn = "0819465615",
volume = "6448",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Fabrication of silicon-based nanoparticles for biological imaging

AU - Zhang, Xiaoming

AU - Neiner, Doinita

AU - Wang, Shizhong

AU - Louie, Angelique Y.

AU - Kauzlarich, Susan M.

PY - 2007

Y1 - 2007

N2 - Fluorescent silicon nanomaterials have initiated great interest for their potential biological applications. In this paper, we report the synthesis of water-soluble, luminescent silicon nanoparticles with high quantum yield. The surfaces of the Si nanoparticles were capped by hydrophobic or hydrophilic organic molecules that passivate and protect the silicon particles from oxidation. The as-synthesized silicon nanoparticles displayed strong photoluminescence in the blue region of the visible spectrum. The attached organic molecules conveyed both water solubility and high stability, and coating had little adverse effect on the optical properties of nanoparticles. These results have major implications towards using colloidal silicon nanoparticles effectively in biological fluorescence imaging.

AB - Fluorescent silicon nanomaterials have initiated great interest for their potential biological applications. In this paper, we report the synthesis of water-soluble, luminescent silicon nanoparticles with high quantum yield. The surfaces of the Si nanoparticles were capped by hydrophobic or hydrophilic organic molecules that passivate and protect the silicon particles from oxidation. The as-synthesized silicon nanoparticles displayed strong photoluminescence in the blue region of the visible spectrum. The attached organic molecules conveyed both water solubility and high stability, and coating had little adverse effect on the optical properties of nanoparticles. These results have major implications towards using colloidal silicon nanoparticles effectively in biological fluorescence imaging.

KW - Fluorescence imaging

KW - Photo luminescence

KW - Silicon

KW - Water-soluble

UR - http://www.scopus.com/inward/record.url?scp=34548210083&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548210083&partnerID=8YFLogxK

U2 - 10.1117/12.701442

DO - 10.1117/12.701442

M3 - Conference contribution

AN - SCOPUS:34548210083

SN - 0819465615

SN - 9780819465610

VL - 6448

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -