Fabrication and Characterization of PLA-PGA Orthopedic Implants

C. Mauli Agrawal, Gabriele G. Niederauer, Kyriacos A. Athanasiou

Research output: Contribution to journalArticle

67 Scopus citations


Fabrication methods and property characterization of polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers are reviewed. Both of these aliphatic polyesters belong to the a-hydroxy group and biodegrade in a physiological environment to monomeric acids, which are readily processed and excreted from the body. The physical and mechanical characteristics discussed include molecular weight, crystallinity, stress–strain behavior, permeability, and melting/glass transition temperatures. The most common methods of fabricating PLA–PGA materials into medical devices are described.

Original languageEnglish (US)
Pages (from-to)241-252
Number of pages12
JournalTissue Engineering
Issue number3
StatePublished - Sep 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Engineering(all)

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    Agrawal, C. M., Niederauer, G. G., & Athanasiou, K. A. (1995). Fabrication and Characterization of PLA-PGA Orthopedic Implants. Tissue Engineering, 1(3), 241-252. https://doi.org/10.1089/ten.1995.1.241