Eye organogenesis: A hierarchical view of ocular development

Joel B. Miesfeld, Nadean L Brown

Research output: Contribution to journalArticlepeer-review

Abstract

This chapter provides an overview of the early developmental origins of six ocular tissues: the cornea, lens, ciliary body, iris, neural retina, and retina pigment epithelium. Many of these tissue types are concurrently specified and undergo a complex set of morphogenetic movements that facilitate their structural interconnection. Within the context of vertebrate eye organogenesis, we also discuss the genetic hierarchies of transcription factors and signaling pathways that regulate growth, patterning, cell type specification and differentiation.

Original languageEnglish (US)
JournalCurrent Topics in Developmental Biology
DOIs
StateAccepted/In press - Jan 1 2019

Keywords

  • Ciliary body
  • Cornea
  • Iris
  • Lens
  • Ocular development
  • Retina
  • Retinal pigmented epithelium

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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