Extreme Plasma Dilution Decreases Heparin and Protamine Cardiopulmonary Bypass Requirements: A Case Report on a Jehovah's Witness Patient

Emilie Chang, Jason W. Gatling, Scott Bode, Paul C. Herrmann, Brian S. Bull, Richard L. Applegate

Research output: Contribution to journalArticle

Abstract

The primary focus of cardiopulmonary bypass management in Jehovah's Witness patients is the need to conserve blood. A consequence of these strategies inevitably results in hemodilution that is frequently extreme enough to dilute clotting factors and potentially impair coagulation. The purpose of this case report is to demonstrate that a hemodiluted patient requires less heparin to sustain anticoagulation and less protamine to reverse heparin at cardiopulmonary bypass termination. Patient harm may ensue unless the effects of extreme hemodilution are recognized.

Original languageEnglish (US)
Pages (from-to)291-293
Number of pages3
JournalA & A case reports
Volume8
Issue number11
DOIs
StatePublished - Jun 1 2017

ASJC Scopus subject areas

  • Medicine(all)

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