Extragastric Manifestations of Helicobacter pylori Infection - Other Helicobacter Species

Jay V Solnick, Francesco Franceschi, D. Roccarina, Antonio Gasbarrini

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Recent studies have indicated a strong link between Helicobacter pylori and idiopathic thrombocytopenic purpura and iron deficiency anemia. Interesting results have also been obtained for ischemic heart disease, though most putative associations between H. pylori infection and extragastric disease remain speculative. With regard to other Helicobacter species, Helicobacter felis has been shown to play a role in gastric carcinogenesis in mouse models. An increased susceptibility to cholesterol gallstone formation has been described in animals fed a lithogenic diet and infected with Helicobacter bilis, or co-infected with Helicobacter hepaticus and Helicobacter rodentium. Finally, enterohepatic Helicobacter species have also been exploited to better understand inflammatory bowel disease.

Original languageEnglish (US)
Pages (from-to)46-51
Number of pages6
Issue numberSUPPL.1
StatePublished - Oct 2006


  • Anemia
  • Cardiovascular diseases
  • Colorectal cancer
  • Enterohepatic
  • Helicobacters
  • Idiopathic
  • Iron deficiency
  • Thrombocytopenic purpura

ASJC Scopus subject areas

  • Gastroenterology
  • Infectious Diseases
  • Microbiology


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