Extracorporeal renal replacement therapy and blood purification in critical care

Larry D Cowgill, Julien Guillaumin

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Objective: To review indications methods of renal replacement therapies (RRT) and practical considerations for the creation of a RRT program. Data Sources: Current human and veterinary literature review with a focus on advanced renal physiology and clinical experience in RRT and acute/chronic kidney diseases. Data Synthesis: Renal replacement therapies encompass intermittent hemodialysis, continuous renal replacement therapy as well as some "hybrid" techniques. Each method of RRT has practical and theoretical advantages but currently there is no evidence that one technique is superior to the other. Conclusions: RRT is a valuable therapeutic tool for treatment of acute kidney injury and chronic kidney disease. The implementation of an RRT program needs to take into consideration multiple parameters beyond the choice of an RRT platform.

Original languageEnglish (US)
Pages (from-to)194-204
Number of pages11
JournalJournal of Veterinary Emergency and Critical Care
Issue number2
StatePublished - Mar 2013


  • Acute kidney injury
  • Hemodialysis
  • Hemoperfusion
  • Kidney failure
  • Therapeutic plasma exchange

ASJC Scopus subject areas

  • veterinary(all)


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