Extracorporeal membrane oxygenation and high-frequency oscillatory ventilation: potential therapeutic relationships

J. D. Cornish, D. R. Gerstmann, R. H. Clark, J. M. Carter, Donald Null, R. A. DeLemos

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Eighteen neonates 33 to 42 wk gestational age with severe respiratory failure were referred for extracorporeal membrane oxygenation (ECMO). Sixteen ultimately met the ECMO criteria, of whom 15 were first offered high-frequency oscillatory ventilation (HFOV). Seven responded to HFOV alone and did not require ECMO treatment. Eight of the nine remaining patients were placed on ECMO support with HOFV. Infants who responded to HFOV alone tended to have pneumonia more than meconium aspiration, to be smaller and more immature, to have higher Apgar scores, and to have suffered severe hypoxia (alveolar-arterial oxygen pressure difference over 600 torr) for less time than the ECMO group. Although patient numbers are small, a trend is noted which favors HFOV treatment alone in terms of the duration of HFOV, the total duration of assisted ventilation, the rapidity with which extubation was accomplished, and the length of hospital stay.

Original languageEnglish (US)
Pages (from-to)831-834
Number of pages4
JournalCritical Care Medicine
Volume15
Issue number9
DOIs
StatePublished - Jan 1 1987
Externally publishedYes

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High-Frequency Ventilation
Extracorporeal Membrane Oxygenation
Length of Stay
Meconium Aspiration Syndrome
Therapeutics
Apgar Score
Respiratory Insufficiency
Gestational Age
Ventilation
Pneumonia
Arterial Pressure
Newborn Infant
Oxygen

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Extracorporeal membrane oxygenation and high-frequency oscillatory ventilation : potential therapeutic relationships. / Cornish, J. D.; Gerstmann, D. R.; Clark, R. H.; Carter, J. M.; Null, Donald; DeLemos, R. A.

In: Critical Care Medicine, Vol. 15, No. 9, 01.01.1987, p. 831-834.

Research output: Contribution to journalArticle

Cornish, J. D. ; Gerstmann, D. R. ; Clark, R. H. ; Carter, J. M. ; Null, Donald ; DeLemos, R. A. / Extracorporeal membrane oxygenation and high-frequency oscillatory ventilation : potential therapeutic relationships. In: Critical Care Medicine. 1987 ; Vol. 15, No. 9. pp. 831-834.
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