TY - JOUR
T1 - Extracellular space in chickens estimated using sucrose, thiosulfate, and thiocyanate injected concurrently
AU - Danby, R.
AU - Curry, F. E.
AU - Gibson, W. R.
PY - 1980
Y1 - 1980
N2 - The extracellular fluid (ECF) volume was estimated in chickens, a species for which remarkably high estimates (usually of thiocyanate space) have been reported. Chickens aged 8 weeks were given a single intravenous injection containing the three extracellular markers, [3H]sucrose, [35S]thiosulfate, and thiocyanate. After allowing 10 min for mixing to occur, plasma samples were obtained at intervals and marker concentrations were measured and used to estimate initial dilution of the markers in ECF. In contrast with most earlier studies, all three markers yielded estimates of ECF volumes that were in the range normally found in mammals. The mean sucrose space (17.8 ml/100 g body wt) was significantly lower than both the thiosulfate space (22.3 ml/100 g) and the thiocyanate space (23.9 ml/100 g).
AB - The extracellular fluid (ECF) volume was estimated in chickens, a species for which remarkably high estimates (usually of thiocyanate space) have been reported. Chickens aged 8 weeks were given a single intravenous injection containing the three extracellular markers, [3H]sucrose, [35S]thiosulfate, and thiocyanate. After allowing 10 min for mixing to occur, plasma samples were obtained at intervals and marker concentrations were measured and used to estimate initial dilution of the markers in ECF. In contrast with most earlier studies, all three markers yielded estimates of ECF volumes that were in the range normally found in mammals. The mean sucrose space (17.8 ml/100 g body wt) was significantly lower than both the thiosulfate space (22.3 ml/100 g) and the thiocyanate space (23.9 ml/100 g).
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M3 - Article
C2 - 7403103
AN - SCOPUS:0019311377
VL - 164
SP - 336
EP - 340
JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
SN - 1535-3702
IS - 3
ER -