Extracellular matrix proteins promote chondrocyte attachment on PLA/PGA copolymer scaffolds

B. C. Shih, M. Lopez-Cruzan, C. M. Agrawal, K. A. Athanasiou, R. G. LeBaron

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Osteoarthritis is a complex disease with a common endstage of cartilage degeneration and failure. Aging, trauma, and genetics may initiate a process leading to change in the metabolism and composition of the cartilage. The result is often further abnormalities in cartilage function, biomechanics and morphology. Advance stages of the disease result in loss of cartilage. The viability of using chrondocytes together with biomaterial cell carriers as grafts for repair of cartilage defects was studied. The effect of cell attachment proteins have on the cell attachment properties of synthetic material was evaluated.

Original languageEnglish (US)
Title of host publicationSouthern Biomedical Engineering Conference - Proceedings
Place of PublicationPiscataway, NJ, United States
PublisherIEEE
Pages67
Number of pages1
StatePublished - 1998
Externally publishedYes
EventProceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA
Duration: Feb 6 1998Feb 8 1998

Other

OtherProceedings of the 1998 17th Southern Biomedical Engineering Conference
CitySan Antonio, TX, USA
Period2/6/982/8/98

ASJC Scopus subject areas

  • Engineering(all)

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