Extracellular matrix proteins promote chondrocyte attachment on PLA/PGA copolymer scaffolds

B. C. Shih; M. Lopez-Cruzan; C. M. Agrawal; K. A. Athanasiou; R. G. LeBaron

Extracellular matrix proteins promote chondrocyte attachment on PLA/PGA copolymer scaffolds

B. C. Shih, M. Lopez-Cruzan, C. M. Agrawal, K. A. Athanasiou, R. G. LeBaron

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Osteoarthritis is a complex disease with a common endstage of cartilage degeneration and failure. Aging, trauma, and genetics may initiate a process leading to change in the metabolism and composition of the cartilage. The result is often further abnormalities in cartilage function, biomechanics and morphology. Advance stages of the disease result in loss of cartilage. The viability of using chrondocytes together with biomaterial cell carriers as grafts for repair of cartilage defects was studied. The effect of cell attachment proteins have on the cell attachment properties of synthetic material was evaluated.

Original language	English (US)
Title of host publication	Southern Biomedical Engineering Conference - Proceedings
Place of Publication	Piscataway, NJ, United States
Publisher	IEEE
Pages	67
Number of pages	1
State	Published - 1998
Externally published	Yes
Event	Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998

Other

Other	Proceedings of the 1998 17th Southern Biomedical Engineering Conference
City	San Antonio, TX, USA
Period	2/6/98 → 2/8/98

ASJC Scopus subject areas

Engineering(all)

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Extracellular matrix proteins promote chondrocyte attachment on PLA/PGA copolymer scaffolds. / Shih, B. C.; Lopez-Cruzan, M.; Agrawal, C. M.; Athanasiou, K. A.; LeBaron, R. G.

Southern Biomedical Engineering Conference - Proceedings. Piscataway, NJ, United States : IEEE, 1998. p. 67.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Shih, BC, Lopez-Cruzan, M, Agrawal, CM, Athanasiou, KA & LeBaron, RG 1998, Extracellular matrix proteins promote chondrocyte attachment on PLA/PGA copolymer scaffolds. in Southern Biomedical Engineering Conference - Proceedings. IEEE, Piscataway, NJ, United States, pp. 67, Proceedings of the 1998 17th Southern Biomedical Engineering Conference, San Antonio, TX, USA, 2/6/98.

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AU - LeBaron, R. G.

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AB - Osteoarthritis is a complex disease with a common endstage of cartilage degeneration and failure. Aging, trauma, and genetics may initiate a process leading to change in the metabolism and composition of the cartilage. The result is often further abnormalities in cartilage function, biomechanics and morphology. Advance stages of the disease result in loss of cartilage. The viability of using chrondocytes together with biomaterial cell carriers as grafts for repair of cartilage defects was studied. The effect of cell attachment proteins have on the cell attachment properties of synthetic material was evaluated.

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