Extensive coronary thrombosis in thrombotic-thrombocytopenic purpura

D. Hasper, D. Schrage, S. Niesporek, Friedrich D Knollmann, D. Barckow, M. Oppert

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


We describe a case of a 41-year-old female patient who was admitted with typical signs of thrombotic-thrombocytopenic purpura. Markers of myocardial ischemia (Troponin T, CK, CK-MB) were even present at admission without symptoms of angina pectoris. Only a few hours after admission the patient developed all signs of cardiogenic shock with subsequently cardiac arrest. Postmortal coronary angiographies showed occlusions in all coronary arteries with significant myocardial necrosis. We are unaware of any report that describes macrovascular occlusions in thrombotic-thrombocytopenic purpura.

Original languageEnglish (US)
Pages (from-to)407-409
Number of pages3
JournalInternational Journal of Cardiology
Issue number3
StatePublished - Jan 26 2006
Externally publishedYes


  • Cardiogenic shock
  • Myocardial infarction
  • Thrombotic-thrombocytopenic purpura

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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