Abstract
The expression of ten tuberculosis candidate genes in lung and lymph nodes of cynomologus macaques vaccinated and experimentally infected with Mycobacterium tuberculosis (Mtb) was quantified. The expression of TNFα, IL10, IL1β, TLR4, IL17, IL6, IL12, and iNOS in the lungs of vaccinated animals was higher than that of non-vaccinated animals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 161-164 |
| Number of pages | 4 |
| Journal | Journal of Medical Primatology |
| Volume | 42 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 2013 |
Keywords
- Cynomolgus macaques
- Gene expression
- IL12
- IL17
- INOS
- Tuberculosis
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
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Cite this
Roodgar, M., Lackner, A., Kaushal, D., Sankaran-Walters, S., Dandekar, S., Satkoski Trask, J., Drake, C., & Smith, D. G. (2013). Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques. Journal of Medical Primatology, 42(3), 161-164. https://doi.org/10.1111/jmp.12040