Exposure time dependence of image quality in high-speed retinal in vivo Fourier-domain OCT

Robert Zawadzki, Bradley A. Bower, Mingtao Zhao, Marinko Sarunic, Sophie Laut, John S Werner, Joseph A. Izatt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations


We built a Fourier domain optical coherence tomography (FD-OCT) system using a line scan CCD camera that allows real time data display and acquisition. This instrument is able to produce 2D B-scans as well as 3D data sets with human subjects in vivo in clinical settings. In this paper we analyze the influence of varying exposure times of the CCD detector on image quality. Sensitivity values derived from theoretical predictions have been compared with measurements (obtained with mirrors and neutral density filters placed in both interferometer arms). The results of these experiments, discussion about differences between sensitivity values, potential sources of discrepancies, and recommendations for optimal exposure times will be described in this paper. A short discussion of observed artifacts as well as possible ways to remove them is presented. The influence of relative retinal position with respect to reference mirror position will also be described.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
EditorsF. Manns, P.G. Soederberg, A. Ho, B.E. Stuck, M. Belkin
Number of pages8
StatePublished - 2005
EventOphtalmic Technologies XV - San Jose, CA, United States
Duration: Jan 22 2005Jan 25 2005


OtherOphtalmic Technologies XV
Country/TerritoryUnited States
CitySan Jose, CA


  • Digital image processing
  • Imaging systems
  • Medical and biomedical imaging
  • Ophthalmology
  • Optical coherence tomography

ASJC Scopus subject areas

  • Engineering(all)


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