Expert opinion: What to do when there is coccidioides exposure in a laboratory

David A. Stevens, Karl V. Demons, Hiiiei B. Levine, Demosthenes Pappagianis, Ellen Jo Baron, John R. Hamilton, Stanley C. Deresinski, Nancy Johnson

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Inadvertent exposure to Coccidioides species by laboratory staff and others as a result of a mishap is not an uncommon cause of infection in clinical microbiology laboratories. These types of infection may occur in laboratories outside the endemic areas, because the etiologic agent is unexpected in the submitted specimens and because personnel may be unfamiliar with the hazards of dealing with Coccidioides species in the laboratory. Coccidioidal infections are often difficult to treat, and outcomes can be poor. Here, we emphasize prevention and an approach to a laboratory accident that minimizes the risk of exposure to laboratory staff and staff in adjacent areas. On the basis of an artificially large exposure to arthroconidia that may occur as a result of a laboratory accident, a conservative approach of close observation and early treatment of exposed staff is discussed.

Original languageEnglish (US)
Pages (from-to)919-923
Number of pages5
JournalClinical Infectious Diseases
Issue number6
StatePublished - Sep 15 2009

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)


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