Expert opinion: What to do when there is coccidioides exposure in a laboratory

David A. Stevens, Karl V. Demons, Hiiiei B. Levine, Demosthenes Pappagianis, Ellen Jo Baron, John R. Hamilton, Stanley C. Deresinski, Nancy Johnson

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Inadvertent exposure to Coccidioides species by laboratory staff and others as a result of a mishap is not an uncommon cause of infection in clinical microbiology laboratories. These types of infection may occur in laboratories outside the endemic areas, because the etiologic agent is unexpected in the submitted specimens and because personnel may be unfamiliar with the hazards of dealing with Coccidioides species in the laboratory. Coccidioidal infections are often difficult to treat, and outcomes can be poor. Here, we emphasize prevention and an approach to a laboratory accident that minimizes the risk of exposure to laboratory staff and staff in adjacent areas. On the basis of an artificially large exposure to arthroconidia that may occur as a result of a laboratory accident, a conservative approach of close observation and early treatment of exposed staff is discussed.

Original languageEnglish (US)
Pages (from-to)919-923
Number of pages5
JournalClinical Infectious Diseases
Volume49
Issue number6
DOIs
StatePublished - Sep 15 2009

Fingerprint

Coccidioides
Expert Testimony
Accidents
Infection
Microbiology
Observation

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

Stevens, D. A., Demons, K. V., Levine, H. B., Pappagianis, D., Baron, E. J., Hamilton, J. R., ... Johnson, N. (2009). Expert opinion: What to do when there is coccidioides exposure in a laboratory. Clinical Infectious Diseases, 49(6), 919-923. https://doi.org/10.1086/605441

Expert opinion : What to do when there is coccidioides exposure in a laboratory. / Stevens, David A.; Demons, Karl V.; Levine, Hiiiei B.; Pappagianis, Demosthenes; Baron, Ellen Jo; Hamilton, John R.; Deresinski, Stanley C.; Johnson, Nancy.

In: Clinical Infectious Diseases, Vol. 49, No. 6, 15.09.2009, p. 919-923.

Research output: Contribution to journalArticle

Stevens, DA, Demons, KV, Levine, HB, Pappagianis, D, Baron, EJ, Hamilton, JR, Deresinski, SC & Johnson, N 2009, 'Expert opinion: What to do when there is coccidioides exposure in a laboratory', Clinical Infectious Diseases, vol. 49, no. 6, pp. 919-923. https://doi.org/10.1086/605441
Stevens, David A. ; Demons, Karl V. ; Levine, Hiiiei B. ; Pappagianis, Demosthenes ; Baron, Ellen Jo ; Hamilton, John R. ; Deresinski, Stanley C. ; Johnson, Nancy. / Expert opinion : What to do when there is coccidioides exposure in a laboratory. In: Clinical Infectious Diseases. 2009 ; Vol. 49, No. 6. pp. 919-923.
@article{904daf7ab1de42cdb574986fc2deb785,
title = "Expert opinion: What to do when there is coccidioides exposure in a laboratory",
abstract = "Inadvertent exposure to Coccidioides species by laboratory staff and others as a result of a mishap is not an uncommon cause of infection in clinical microbiology laboratories. These types of infection may occur in laboratories outside the endemic areas, because the etiologic agent is unexpected in the submitted specimens and because personnel may be unfamiliar with the hazards of dealing with Coccidioides species in the laboratory. Coccidioidal infections are often difficult to treat, and outcomes can be poor. Here, we emphasize prevention and an approach to a laboratory accident that minimizes the risk of exposure to laboratory staff and staff in adjacent areas. On the basis of an artificially large exposure to arthroconidia that may occur as a result of a laboratory accident, a conservative approach of close observation and early treatment of exposed staff is discussed.",
author = "Stevens, {David A.} and Demons, {Karl V.} and Levine, {Hiiiei B.} and Demosthenes Pappagianis and Baron, {Ellen Jo} and Hamilton, {John R.} and Deresinski, {Stanley C.} and Nancy Johnson",
year = "2009",
month = "9",
day = "15",
doi = "10.1086/605441",
language = "English (US)",
volume = "49",
pages = "919--923",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "6",

}

TY - JOUR

T1 - Expert opinion

T2 - What to do when there is coccidioides exposure in a laboratory

AU - Stevens, David A.

AU - Demons, Karl V.

AU - Levine, Hiiiei B.

AU - Pappagianis, Demosthenes

AU - Baron, Ellen Jo

AU - Hamilton, John R.

AU - Deresinski, Stanley C.

AU - Johnson, Nancy

PY - 2009/9/15

Y1 - 2009/9/15

N2 - Inadvertent exposure to Coccidioides species by laboratory staff and others as a result of a mishap is not an uncommon cause of infection in clinical microbiology laboratories. These types of infection may occur in laboratories outside the endemic areas, because the etiologic agent is unexpected in the submitted specimens and because personnel may be unfamiliar with the hazards of dealing with Coccidioides species in the laboratory. Coccidioidal infections are often difficult to treat, and outcomes can be poor. Here, we emphasize prevention and an approach to a laboratory accident that minimizes the risk of exposure to laboratory staff and staff in adjacent areas. On the basis of an artificially large exposure to arthroconidia that may occur as a result of a laboratory accident, a conservative approach of close observation and early treatment of exposed staff is discussed.

AB - Inadvertent exposure to Coccidioides species by laboratory staff and others as a result of a mishap is not an uncommon cause of infection in clinical microbiology laboratories. These types of infection may occur in laboratories outside the endemic areas, because the etiologic agent is unexpected in the submitted specimens and because personnel may be unfamiliar with the hazards of dealing with Coccidioides species in the laboratory. Coccidioidal infections are often difficult to treat, and outcomes can be poor. Here, we emphasize prevention and an approach to a laboratory accident that minimizes the risk of exposure to laboratory staff and staff in adjacent areas. On the basis of an artificially large exposure to arthroconidia that may occur as a result of a laboratory accident, a conservative approach of close observation and early treatment of exposed staff is discussed.

UR - http://www.scopus.com/inward/record.url?scp=70049112665&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70049112665&partnerID=8YFLogxK

U2 - 10.1086/605441

DO - 10.1086/605441

M3 - Article

C2 - 19663562

AN - SCOPUS:70049112665

VL - 49

SP - 919

EP - 923

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - 6

ER -