Experimental validation of Monte Carlo dose calculations about a high- intensity Ir-192 source for pulsed dose-rate brachytherapy

Richard K Valicenti, A. S. Kirov, A. S. Meigooni, V. Mishra, R. K. Das, J. F. Williamson

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Despite widespread use of high-intensity Ir-192 remotely afterloaded sources, no published measured or calculated dose-rate tables for currently used source designs are available. For a pulsed dose-rate Ir-192 source, both transverse axis (0.5-10 cm) and two-dimensional polar dose-rate profiles (1.5, 3, and 5 cm) were measured with thermoluminescent dosimetry in a solid water phantom. Dose rates were normalized to measured air-kerma strength, and the source geometry was verified by pinhole autoradiography and transmission radiography. At each measurement point, dose rates were calculated by a Monte Carlo photon transport (MCPT) code, which realistically modeled the experimental phantom, source, and detector geometry. Agreement between MCPT absolute dose-rate calculations and measurements averaged 3% and was less than 5%, demonstrating that Monte Carlo simulation is an accurate and powerful tool for two-dimensional dosimetric characterization of high activity Ir-192 sources.

Original languageEnglish (US)
Pages (from-to)821-829
Number of pages9
JournalMedical Physics
Volume22
Issue number6
DOIs
StatePublished - 1995
Externally publishedYes

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Brachytherapy
Photons
Thermoluminescent Dosimetry
Autoradiography
Radiography
Air
Water

Keywords

  • Ir
  • Monte Carlo
  • pulsed dose rate
  • thermoluminescent dosimetry

ASJC Scopus subject areas

  • Biophysics

Cite this

Experimental validation of Monte Carlo dose calculations about a high- intensity Ir-192 source for pulsed dose-rate brachytherapy. / Valicenti, Richard K; Kirov, A. S.; Meigooni, A. S.; Mishra, V.; Das, R. K.; Williamson, J. F.

In: Medical Physics, Vol. 22, No. 6, 1995, p. 821-829.

Research output: Contribution to journalArticle

Valicenti, Richard K ; Kirov, A. S. ; Meigooni, A. S. ; Mishra, V. ; Das, R. K. ; Williamson, J. F. / Experimental validation of Monte Carlo dose calculations about a high- intensity Ir-192 source for pulsed dose-rate brachytherapy. In: Medical Physics. 1995 ; Vol. 22, No. 6. pp. 821-829.
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