Experimental transmission of Ehrlichia equi to horses through naturally infected ticks (Ixodes pacificus) from Northern California

G. H. Reubel, R. B. Kimsey, J. E. Barlough, John E Madigan

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

We report the experimental transmission of Ehrlichia equi from naturally infected Ixodes pacificus ticks to horses. Three weeks after exposure to ticks, two of three horses developed clinical signs compatible with E. equi infection, while one horse remained asymptomatic. 16S rRNA gene PCR of blood leukocyte lysates was positive for all horses at various time points; two horses seroconverted. The 16S rRNA gene sequences amplified from tick- exposed horses showed more than 99% homology to corresponding fragments of the 16S rRNA genes of E. equi, Ehrlichia phagocytophila, and the human granulocytic ehrlichiosis agent.

Original languageEnglish (US)
Pages (from-to)2131-2134
Number of pages4
JournalJournal of Clinical Microbiology
Volume36
Issue number7
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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