Experimental procedure for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (MRI) radiation dosimetry

C. Baldock, R. P. Burford, N. Billingham, G. S. Wagner, S. Patval, Ramsey D Badawi, S. F. Keevil

Research output: Contribution to journalArticle

169 Citations (Scopus)

Abstract

A simple methodology for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (MRI) radiation dosimetry is presented to enable individuals to undertake such work in a routine clinical environment. Samples of PAG were irradiated using a linear accelerator and imaged using a 0.5 T (22 MHz) Philips Gyroscan MRI scanner. The mean spin-lattice relaxation rate was measured using a 'turbo-mixed' sequence, consisting of a series of 90°pulses, each followed by acquisition of a train of spin echoes. The mean sensitivity for five different batches of PAG in the range up to 10 Gy was calculated to be 0.0285 s-1 Gy-1 for the mean spin-lattice relaxation rate with a percentage standard deviation of 1.25%. The overall reproducibility between batches was calculated to be 2.69%. This methodology, which introduces the novel use of pre-filled nitrogen vials for calibration, has been used to develop techniques for filling anatomically shaped anthropomorphic phantoms.

Original languageEnglish (US)
Pages (from-to)695-702
Number of pages8
JournalPhysics in Medicine and Biology
Volume43
Issue number3
DOIs
StatePublished - 1998
Externally publishedYes

Fingerprint

Radiometry
Magnetic resonance
Polyacrylates
Calibration
Dosimetry
dosimeters
magnetic resonance
Spin-lattice relaxation
Gels
Magnetic Resonance Imaging
gels
Imaging techniques
spin-lattice relaxation
radiation
methodology
Particle Accelerators
Linear accelerators
linear accelerators
scanners
standard deviation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Physics and Astronomy (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Experimental procedure for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (MRI) radiation dosimetry. / Baldock, C.; Burford, R. P.; Billingham, N.; Wagner, G. S.; Patval, S.; Badawi, Ramsey D; Keevil, S. F.

In: Physics in Medicine and Biology, Vol. 43, No. 3, 1998, p. 695-702.

Research output: Contribution to journalArticle

Baldock, C. ; Burford, R. P. ; Billingham, N. ; Wagner, G. S. ; Patval, S. ; Badawi, Ramsey D ; Keevil, S. F. / Experimental procedure for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (MRI) radiation dosimetry. In: Physics in Medicine and Biology. 1998 ; Vol. 43, No. 3. pp. 695-702.
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