Experimental Lyme arthritis in rats infected with Borrelia burgdorferi

Stephen W Barthold, K. D. Moody, G. A. Terwilliger, P. H. Duray, R. O. Jacoby, A. C. Steere

Research output: Contribution to journalArticle

92 Scopus citations


In an effort to find an animal model of Lyme arthritis, we initially examined the susceptibility of LEW/N rats to B. burgdorferi infection because of their predisposition to bacterial cell wall-induced arthritis. We report here that live B. burgdorferi induced arthritis in two inbred rat strains and one outbred rat stock.

Original languageEnglish (US)
Pages (from-to)842-846
Number of pages5
JournalJournal of Infectious Diseases
Issue number4
StatePublished - 1988
Externally publishedYes


ASJC Scopus subject areas

  • Immunology
  • Public Health, Environmental and Occupational Health

Cite this

Barthold, S. W., Moody, K. D., Terwilliger, G. A., Duray, P. H., Jacoby, R. O., & Steere, A. C. (1988). Experimental Lyme arthritis in rats infected with Borrelia burgdorferi. Journal of Infectious Diseases, 157(4), 842-846.