Experimental internuclear ophthalmoplegia

R. M. Burde, R. A W Lehman, G. Roper Hall, J. Brooks, John L Keltner

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A midline experimental lesion separating the medial longitudinal fasciculi at and below the level of the abducens nuclei without damaging either fasciculus at the level of the nuclei has produced defects of ocular motility resembling those of clinical internuclear ophthalmoplegia. Electromyographic recordings during lateral gaze demonstrate: lack of inhibition of the lateral rectus muscle in the adducting eye, delayed inhibition of the medial rectus muscle in the abducting eye, and occasional evidence of excitation of the medial rectus muscle of the abducting eye probably associated with pupillary constriction. The presumed physiologic mechanisms involved in conjugate gaze movements are discussed in the light of the experimental findings.

Original languageEnglish (US)
Pages (from-to)233-239
Number of pages7
JournalBritish Journal of Ophthalmology
Volume61
Issue number3
StatePublished - 1977

Fingerprint

Ocular Motility Disorders
Muscles
Constriction

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Burde, R. M., Lehman, R. A. W., Roper Hall, G., Brooks, J., & Keltner, J. L. (1977). Experimental internuclear ophthalmoplegia. British Journal of Ophthalmology, 61(3), 233-239.

Experimental internuclear ophthalmoplegia. / Burde, R. M.; Lehman, R. A W; Roper Hall, G.; Brooks, J.; Keltner, John L.

In: British Journal of Ophthalmology, Vol. 61, No. 3, 1977, p. 233-239.

Research output: Contribution to journalArticle

Burde, RM, Lehman, RAW, Roper Hall, G, Brooks, J & Keltner, JL 1977, 'Experimental internuclear ophthalmoplegia', British Journal of Ophthalmology, vol. 61, no. 3, pp. 233-239.
Burde RM, Lehman RAW, Roper Hall G, Brooks J, Keltner JL. Experimental internuclear ophthalmoplegia. British Journal of Ophthalmology. 1977;61(3):233-239.
Burde, R. M. ; Lehman, R. A W ; Roper Hall, G. ; Brooks, J. ; Keltner, John L. / Experimental internuclear ophthalmoplegia. In: British Journal of Ophthalmology. 1977 ; Vol. 61, No. 3. pp. 233-239.
@article{456ecf77d8ca4850b4eaaa200df2bf83,
title = "Experimental internuclear ophthalmoplegia",
abstract = "A midline experimental lesion separating the medial longitudinal fasciculi at and below the level of the abducens nuclei without damaging either fasciculus at the level of the nuclei has produced defects of ocular motility resembling those of clinical internuclear ophthalmoplegia. Electromyographic recordings during lateral gaze demonstrate: lack of inhibition of the lateral rectus muscle in the adducting eye, delayed inhibition of the medial rectus muscle in the abducting eye, and occasional evidence of excitation of the medial rectus muscle of the abducting eye probably associated with pupillary constriction. The presumed physiologic mechanisms involved in conjugate gaze movements are discussed in the light of the experimental findings.",
author = "Burde, {R. M.} and Lehman, {R. A W} and {Roper Hall}, G. and J. Brooks and Keltner, {John L}",
year = "1977",
language = "English (US)",
volume = "61",
pages = "233--239",
journal = "British Journal of Ophthalmology",
issn = "0007-1161",
publisher = "BMJ Publishing Group",
number = "3",

}

TY - JOUR

T1 - Experimental internuclear ophthalmoplegia

AU - Burde, R. M.

AU - Lehman, R. A W

AU - Roper Hall, G.

AU - Brooks, J.

AU - Keltner, John L

PY - 1977

Y1 - 1977

N2 - A midline experimental lesion separating the medial longitudinal fasciculi at and below the level of the abducens nuclei without damaging either fasciculus at the level of the nuclei has produced defects of ocular motility resembling those of clinical internuclear ophthalmoplegia. Electromyographic recordings during lateral gaze demonstrate: lack of inhibition of the lateral rectus muscle in the adducting eye, delayed inhibition of the medial rectus muscle in the abducting eye, and occasional evidence of excitation of the medial rectus muscle of the abducting eye probably associated with pupillary constriction. The presumed physiologic mechanisms involved in conjugate gaze movements are discussed in the light of the experimental findings.

AB - A midline experimental lesion separating the medial longitudinal fasciculi at and below the level of the abducens nuclei without damaging either fasciculus at the level of the nuclei has produced defects of ocular motility resembling those of clinical internuclear ophthalmoplegia. Electromyographic recordings during lateral gaze demonstrate: lack of inhibition of the lateral rectus muscle in the adducting eye, delayed inhibition of the medial rectus muscle in the abducting eye, and occasional evidence of excitation of the medial rectus muscle of the abducting eye probably associated with pupillary constriction. The presumed physiologic mechanisms involved in conjugate gaze movements are discussed in the light of the experimental findings.

UR - http://www.scopus.com/inward/record.url?scp=0017355158&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017355158&partnerID=8YFLogxK

M3 - Article

VL - 61

SP - 233

EP - 239

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

SN - 0007-1161

IS - 3

ER -