Experimental infection of dogs with various Bartonella species or subspecies isolated from their natural reservoir

Bruno B Chomel, Richard W. Ermel, Rickie W. Kasten, Jennifer B. Henn, Drew A. Fleischman, Chao Chin Chang

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Dogs can be infected by a wide variety of Bartonella species. However, limited data is available on experimental infection of dogs with Bartonella strains isolated from domestic animals or wildlife. We report the inoculation of six dogs with Bartonella henselae (feline strain 94022, 16S rRNA type II) in three sets of two dogs, each receiving a different inoculum dose), four dogs inoculated with B. vinsonii subsp. berkhoffii type I (ATCC strain, one mongrel dog) or type II (coyote strain, two beagles and one mongrel) and B. rochalimae (coyote strain, two beagles). None of the dogs inoculated with B. henselae became bacteremic, as detected by classical blood culture. However, several dogs developed severe necrotic lesions at the inoculation site and all six dogs seroconverted within one to two weeks. All dogs inoculated with the B. v. berkhoffii and B. rochalimae strains became bacteremic at levels comparable to previous experimental infections with either a dog isolate or a human isolate. Our data support that dogs are likely accidental hosts for B. henselae, just like humans, and are efficient reservoirs for both B. v. berkhoffii and B. rochalimae.

Original languageEnglish (US)
Pages (from-to)169-176
Number of pages8
JournalVeterinary Microbiology
Volume168
Issue number1
DOIs
StatePublished - Jan 10 2014

Fingerprint

Bartonella
Dogs
dogs
Infection
infection
Bartonella henselae
Coyotes
Canis latrans
Beagle
Felidae
Domestic Animals
domestic animals
lesions (animal)

Keywords

  • Bartonella
  • Dogs
  • Experimental infection
  • Zoonosis

ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

Cite this

Experimental infection of dogs with various Bartonella species or subspecies isolated from their natural reservoir. / Chomel, Bruno B; Ermel, Richard W.; Kasten, Rickie W.; Henn, Jennifer B.; Fleischman, Drew A.; Chang, Chao Chin.

In: Veterinary Microbiology, Vol. 168, No. 1, 10.01.2014, p. 169-176.

Research output: Contribution to journalArticle

Chomel, Bruno B ; Ermel, Richard W. ; Kasten, Rickie W. ; Henn, Jennifer B. ; Fleischman, Drew A. ; Chang, Chao Chin. / Experimental infection of dogs with various Bartonella species or subspecies isolated from their natural reservoir. In: Veterinary Microbiology. 2014 ; Vol. 168, No. 1. pp. 169-176.
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