Abstract
Dogs can be infected by a wide variety of Bartonella species. However, limited data is available on experimental infection of dogs with Bartonella strains isolated from domestic animals or wildlife. We report the inoculation of six dogs with Bartonella henselae (feline strain 94022, 16S rRNA type II) in three sets of two dogs, each receiving a different inoculum dose), four dogs inoculated with B. vinsonii subsp. berkhoffii type I (ATCC strain, one mongrel dog) or type II (coyote strain, two beagles and one mongrel) and B. rochalimae (coyote strain, two beagles). None of the dogs inoculated with B. henselae became bacteremic, as detected by classical blood culture. However, several dogs developed severe necrotic lesions at the inoculation site and all six dogs seroconverted within one to two weeks. All dogs inoculated with the B. v. berkhoffii and B. rochalimae strains became bacteremic at levels comparable to previous experimental infections with either a dog isolate or a human isolate. Our data support that dogs are likely accidental hosts for B. henselae, just like humans, and are efficient reservoirs for both B. v. berkhoffii and B. rochalimae.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 169-176 |
| Number of pages | 8 |
| Journal | Veterinary Microbiology |
| Volume | 168 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 10 2014 |
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Keywords
- Bartonella
- Dogs
- Experimental infection
- Zoonosis
ASJC Scopus subject areas
- Microbiology
- veterinary(all)
Cite this
Experimental infection of dogs with various Bartonella species or subspecies isolated from their natural reservoir. / Chomel, Bruno B; Ermel, Richard W.; Kasten, Rickie W.; Henn, Jennifer B.; Fleischman, Drew A.; Chang, Chao Chin.
In: Veterinary Microbiology, Vol. 168, No. 1, 10.01.2014, p. 169-176.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Experimental infection of dogs with various Bartonella species or subspecies isolated from their natural reservoir
AU - Chomel, Bruno B
AU - Ermel, Richard W.
AU - Kasten, Rickie W.
AU - Henn, Jennifer B.
AU - Fleischman, Drew A.
AU - Chang, Chao Chin
PY - 2014/1/10
Y1 - 2014/1/10
N2 - Dogs can be infected by a wide variety of Bartonella species. However, limited data is available on experimental infection of dogs with Bartonella strains isolated from domestic animals or wildlife. We report the inoculation of six dogs with Bartonella henselae (feline strain 94022, 16S rRNA type II) in three sets of two dogs, each receiving a different inoculum dose), four dogs inoculated with B. vinsonii subsp. berkhoffii type I (ATCC strain, one mongrel dog) or type II (coyote strain, two beagles and one mongrel) and B. rochalimae (coyote strain, two beagles). None of the dogs inoculated with B. henselae became bacteremic, as detected by classical blood culture. However, several dogs developed severe necrotic lesions at the inoculation site and all six dogs seroconverted within one to two weeks. All dogs inoculated with the B. v. berkhoffii and B. rochalimae strains became bacteremic at levels comparable to previous experimental infections with either a dog isolate or a human isolate. Our data support that dogs are likely accidental hosts for B. henselae, just like humans, and are efficient reservoirs for both B. v. berkhoffii and B. rochalimae.
AB - Dogs can be infected by a wide variety of Bartonella species. However, limited data is available on experimental infection of dogs with Bartonella strains isolated from domestic animals or wildlife. We report the inoculation of six dogs with Bartonella henselae (feline strain 94022, 16S rRNA type II) in three sets of two dogs, each receiving a different inoculum dose), four dogs inoculated with B. vinsonii subsp. berkhoffii type I (ATCC strain, one mongrel dog) or type II (coyote strain, two beagles and one mongrel) and B. rochalimae (coyote strain, two beagles). None of the dogs inoculated with B. henselae became bacteremic, as detected by classical blood culture. However, several dogs developed severe necrotic lesions at the inoculation site and all six dogs seroconverted within one to two weeks. All dogs inoculated with the B. v. berkhoffii and B. rochalimae strains became bacteremic at levels comparable to previous experimental infections with either a dog isolate or a human isolate. Our data support that dogs are likely accidental hosts for B. henselae, just like humans, and are efficient reservoirs for both B. v. berkhoffii and B. rochalimae.
KW - Bartonella
KW - Dogs
KW - Experimental infection
KW - Zoonosis
UR - http://www.scopus.com/inward/record.url?scp=84890788347&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84890788347&partnerID=8YFLogxK
U2 - 10.1016/j.vetmic.2013.11.009
DO - 10.1016/j.vetmic.2013.11.009
M3 - Article
C2 - 24315039
AN - SCOPUS:84890788347
VL - 168
SP - 169
EP - 176
JO - Veterinary Microbiology
JF - Veterinary Microbiology
SN - 0378-1135
IS - 1
ER -