Expeditious syntheses of two carbohydrate-linked cisplatin analogs

Yongsheng Chen, Adam Janczuk, Xi Chen, Jianqiang Wang, Mohamad Ksebati, Peng George Wang

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The syntheses of two carbohydrate-linked cisplatin analogs, namely lacto- and α-Gal-cisplatin, are described. A fusion enzymatic approach was used to create the diazido-α-Gal trisaccharide intermediate in the synthesis of α-Gal-cisplatin.

Original languageEnglish (US)
Pages (from-to)1043-1046
Number of pages4
JournalCarbohydrate Research
Volume337
Issue number11
DOIs
StatePublished - Jun 5 2002
Externally publishedYes

Keywords

  • Chemo-enzymatic synthesis
  • Cisplatin analog
  • Fusion enzyme

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry

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  • Cite this

    Chen, Y., Janczuk, A., Chen, X., Wang, J., Ksebati, M., & George Wang, P. (2002). Expeditious syntheses of two carbohydrate-linked cisplatin analogs. Carbohydrate Research, 337(11), 1043-1046. https://doi.org/10.1016/S0008-6215(02)00096-4