Expeditious syntheses of two carbohydrate-linked cisplatin analogs

Yongsheng Chen; Adam Janczuk; Xi Chen; Jianqiang Wang; Mohamad Ksebati; Peng George Wang

doi:10.1016/S0008-6215(02)00096-4

Expeditious syntheses of two carbohydrate-linked cisplatin analogs

Yongsheng Chen, Adam Janczuk, Xi Chen, Jianqiang Wang, Mohamad Ksebati, Peng George Wang

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The syntheses of two carbohydrate-linked cisplatin analogs, namely lacto- and α-Gal-cisplatin, are described. A fusion enzymatic approach was used to create the diazido-α-Gal trisaccharide intermediate in the synthesis of α-Gal-cisplatin.

Original language	English (US)
Pages (from-to)	1043-1046
Number of pages	4
Journal	Carbohydrate Research
Volume	337
Issue number	11
DOIs	https://doi.org/10.1016/S0008-6215(02)00096-4
State	Published - Jun 5 2002
Externally published	Yes

Keywords

Chemo-enzymatic synthesis
Cisplatin analog
Fusion enzyme

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Organic Chemistry

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10.1016/S0008-6215(02)00096-4

Cite this

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title = "Expeditious syntheses of two carbohydrate-linked cisplatin analogs",

abstract = "The syntheses of two carbohydrate-linked cisplatin analogs, namely lacto- and α-Gal-cisplatin, are described. A fusion enzymatic approach was used to create the diazido-α-Gal trisaccharide intermediate in the synthesis of α-Gal-cisplatin.",

keywords = "Chemo-enzymatic synthesis, Cisplatin analog, Fusion enzyme",

author = "Yongsheng Chen and Adam Janczuk and Xi Chen and Jianqiang Wang and Mohamad Ksebati and {George Wang}, Peng",

year = "2002",

month = jun,

day = "5",

doi = "10.1016/S0008-6215(02)00096-4",

language = "English (US)",

volume = "337",

pages = "1043--1046",

journal = "Carbohydrate Research",

issn = "0008-6215",

publisher = "Elsevier BV",

number = "11",

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TY - JOUR

T1 - Expeditious syntheses of two carbohydrate-linked cisplatin analogs

AU - Chen, Yongsheng

AU - Janczuk, Adam

AU - Chen, Xi

AU - Wang, Jianqiang

AU - Ksebati, Mohamad

AU - George Wang, Peng

PY - 2002/6/5

Y1 - 2002/6/5

N2 - The syntheses of two carbohydrate-linked cisplatin analogs, namely lacto- and α-Gal-cisplatin, are described. A fusion enzymatic approach was used to create the diazido-α-Gal trisaccharide intermediate in the synthesis of α-Gal-cisplatin.

AB - The syntheses of two carbohydrate-linked cisplatin analogs, namely lacto- and α-Gal-cisplatin, are described. A fusion enzymatic approach was used to create the diazido-α-Gal trisaccharide intermediate in the synthesis of α-Gal-cisplatin.

KW - Chemo-enzymatic synthesis

KW - Cisplatin analog

KW - Fusion enzyme

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UR - http://www.scopus.com/inward/citedby.url?scp=0037024167&partnerID=8YFLogxK

U2 - 10.1016/S0008-6215(02)00096-4

DO - 10.1016/S0008-6215(02)00096-4

M3 - Article

C2 - 12039546

AN - SCOPUS:0037024167

VL - 337

SP - 1043

EP - 1046

JO - Carbohydrate Research

JF - Carbohydrate Research

SN - 0008-6215

IS - 11

ER -

Expeditious syntheses of two carbohydrate-linked cisplatin analogs

Abstract

Keywords

ASJC Scopus subject areas

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