Abstract
We studied the effects of a single exercise session on lipid and lipoprotein concentrations and on postheparin plasma lipoprotein lipase (LPLA) and hepatic triglyceride hydrolase activities (HTGLA) in 11 trained (T) and ten untrained (UT) men. Subjects exercised on a bicycle ergometer at 80% of their maximal heart rate for one (UT) or two hours (T). Blood samples were drawn 24 hours before and at ten minutes and 24, 48, and 72 hours after exercise. Values were analyzed before and after adjustment for estimated changes in plasma volume (PV). High density lipoprotein cholesterol (HDL-C) increased 2 ± 4 mg/dL in T (P < 0.05) and 1 ± 2 mg/dL in UT subjects beginning 48 hours after exercise. This increase was magnified by adjusting for the 5% to 8% postexercise expansion of PV. The increase in HDL in the T subjects was produced by increases in the HDL2-C subfraction (+3 ± 4 mg/dL, P < 0.05) whereas HDL3 increased in the UT men (+2 ± 3 mg/dL, P < 0.05). LPLA did not change in either subject group when estimated PV changes were ignored but increased 11% (P < 0.05) at 24 hours after exercise when PV was considered. HTGLA was 11% below baseline in the UT men 24 to 72 hours after exercise (P < 0.05) but showed no change in either subject group after adjustment for PV. These results demonstrate that exercise acutely increases HDL levels by raising the HDL2 subfraction in T and the HDL3 subfraction in UT men. Exercise also acutely increases LPLA, but changes in lipase activities may be obscured by concomitant changes in PV. The magnitude of acute changes in lipid, lipoprotein, and lipase values were insufficient to account for the larger differences in these parameters generally noted between T and UT subjects.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 188-192 |
| Number of pages | 5 |
| Journal | Metabolism |
| Volume | 36 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1987 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Exercise acutely increases high density lipoprotein-cholesterol and lipoprotein lipase activity in trained and untrained men. / Kantor, Mark A.; Cullinane, Eileen M.; Sady, Stanley P.; Herbert, Peter N.; Thompson, Paul D.
In: Metabolism, Vol. 36, No. 2, 1987, p. 188-192.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Exercise acutely increases high density lipoprotein-cholesterol and lipoprotein lipase activity in trained and untrained men
AU - Kantor, Mark A.
AU - Cullinane, Eileen M.
AU - Sady, Stanley P.
AU - Herbert, Peter N.
AU - Thompson, Paul D.
PY - 1987
Y1 - 1987
N2 - We studied the effects of a single exercise session on lipid and lipoprotein concentrations and on postheparin plasma lipoprotein lipase (LPLA) and hepatic triglyceride hydrolase activities (HTGLA) in 11 trained (T) and ten untrained (UT) men. Subjects exercised on a bicycle ergometer at 80% of their maximal heart rate for one (UT) or two hours (T). Blood samples were drawn 24 hours before and at ten minutes and 24, 48, and 72 hours after exercise. Values were analyzed before and after adjustment for estimated changes in plasma volume (PV). High density lipoprotein cholesterol (HDL-C) increased 2 ± 4 mg/dL in T (P < 0.05) and 1 ± 2 mg/dL in UT subjects beginning 48 hours after exercise. This increase was magnified by adjusting for the 5% to 8% postexercise expansion of PV. The increase in HDL in the T subjects was produced by increases in the HDL2-C subfraction (+3 ± 4 mg/dL, P < 0.05) whereas HDL3 increased in the UT men (+2 ± 3 mg/dL, P < 0.05). LPLA did not change in either subject group when estimated PV changes were ignored but increased 11% (P < 0.05) at 24 hours after exercise when PV was considered. HTGLA was 11% below baseline in the UT men 24 to 72 hours after exercise (P < 0.05) but showed no change in either subject group after adjustment for PV. These results demonstrate that exercise acutely increases HDL levels by raising the HDL2 subfraction in T and the HDL3 subfraction in UT men. Exercise also acutely increases LPLA, but changes in lipase activities may be obscured by concomitant changes in PV. The magnitude of acute changes in lipid, lipoprotein, and lipase values were insufficient to account for the larger differences in these parameters generally noted between T and UT subjects.
AB - We studied the effects of a single exercise session on lipid and lipoprotein concentrations and on postheparin plasma lipoprotein lipase (LPLA) and hepatic triglyceride hydrolase activities (HTGLA) in 11 trained (T) and ten untrained (UT) men. Subjects exercised on a bicycle ergometer at 80% of their maximal heart rate for one (UT) or two hours (T). Blood samples were drawn 24 hours before and at ten minutes and 24, 48, and 72 hours after exercise. Values were analyzed before and after adjustment for estimated changes in plasma volume (PV). High density lipoprotein cholesterol (HDL-C) increased 2 ± 4 mg/dL in T (P < 0.05) and 1 ± 2 mg/dL in UT subjects beginning 48 hours after exercise. This increase was magnified by adjusting for the 5% to 8% postexercise expansion of PV. The increase in HDL in the T subjects was produced by increases in the HDL2-C subfraction (+3 ± 4 mg/dL, P < 0.05) whereas HDL3 increased in the UT men (+2 ± 3 mg/dL, P < 0.05). LPLA did not change in either subject group when estimated PV changes were ignored but increased 11% (P < 0.05) at 24 hours after exercise when PV was considered. HTGLA was 11% below baseline in the UT men 24 to 72 hours after exercise (P < 0.05) but showed no change in either subject group after adjustment for PV. These results demonstrate that exercise acutely increases HDL levels by raising the HDL2 subfraction in T and the HDL3 subfraction in UT men. Exercise also acutely increases LPLA, but changes in lipase activities may be obscured by concomitant changes in PV. The magnitude of acute changes in lipid, lipoprotein, and lipase values were insufficient to account for the larger differences in these parameters generally noted between T and UT subjects.
UR - http://www.scopus.com/inward/record.url?scp=0023094042&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023094042&partnerID=8YFLogxK
U2 - 10.1016/0026-0495(87)90016-3
DO - 10.1016/0026-0495(87)90016-3
M3 - Article
VL - 36
SP - 188
EP - 192
JO - Metabolism: Clinical and Experimental
JF - Metabolism: Clinical and Experimental
SN - 0026-0495
IS - 2
ER -