Experimental data do not support the idea that excitation-contraction coupling in heart muscle can be explained by a simple calcium-induced calcium release mechanism alone or a simple voltage-dependent calcium release mechanism alone. Our data on excitation-contraction coupling combined with the results of others suggest the need to either develop more complex and more sophisticated single-mechanism models, or to establish dual-control models.
|Original language||English (US)|
|Number of pages||17|
|Journal||Annals of the New York Academy of Sciences|
|State||Published - 1990|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)