Examination of volunteer bias in research involving patients diagnosed with psychogenic nonepileptic seizures

Alex M. Taylor, Deborah Cahn-Weiner, Paul A. Garcia

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

There is some evidence to suggest that the same personality and emotional features observed in patients diagnosed with psychogenic nonepileptic seizures (PNES) may be related to nonparticipation in studies aimed at determining the most effective interventions for treating this patient population. This study aimed to document the frequency with which patients referred to an epilepsy monitoring unit (EMU) for video/EEG telemetry who are diagnosed with PNES or epileptic seizures (ES) participate in survey research. Of the 139 patients approached, 16 patients declined and 23 produced invalid or incomplete surveys. There was no significant difference in participation rates between patients diagnosed with PNES and those diagnosed with ES. These findings argue against a volunteer bias in research involving PNES and suggest that the results of other studies with these patients generalize to the population as a whole.

Original languageEnglish (US)
Pages (from-to)524-526
Number of pages3
JournalEpilepsy and Behavior
Volume15
Issue number4
DOIs
StatePublished - Aug 1 2009
Externally publishedYes

Keywords

  • Clinical trials
  • Epileptic seizures
  • External validity
  • Methodology
  • Psychogenic nonepileptic seizures
  • Volunteer bias

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience

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