Evolutionary implications of horizontal gene transfer

Research output: Contribution to journalArticle

128 Citations (Scopus)

Abstract

The flow of genes between different species represents a form of genetic variation whose implications have not been fully appreciated. Here I examine some key findings on the extent of horizontal gene transfer (HGT) revealed by comparative genome analysis and their theoretical implications. In theoretical terms, HGT affects ideas pertaining to the tree of life, the notion of a last universal common ancestor, and the biological unities, as well as the rules of taxonomic nomenclature. This review discusses the emergence of the eukaryotic cell and the occurrence of HGT among metazoan phyla involving both transposable elements and structural genes for normal housekeeping functions. I also discuss the bacterial pangenome, which provides an important case study on the permeability of species boundaries. An interesting observation about bdelloid rotifers and their reversion to asexual reproduction as it pertains to HGT is included.

Original languageEnglish (US)
Pages (from-to)341-358
Number of pages18
JournalAnnual Review of Genetics
Volume46
DOIs
StatePublished - 2012

Fingerprint

Horizontal Gene Transfer
Asexual Reproduction
DNA Transposable Elements
Gene Flow
Essential Genes
Eukaryotic Cells
Terminology
Permeability
Observation
Genome

ASJC Scopus subject areas

  • Genetics

Cite this

Evolutionary implications of horizontal gene transfer. / Syvanen, Michael.

In: Annual Review of Genetics, Vol. 46, 2012, p. 341-358.

Research output: Contribution to journalArticle

@article{e66ee5b83c50473eb5922178dff98f18,
title = "Evolutionary implications of horizontal gene transfer",
abstract = "The flow of genes between different species represents a form of genetic variation whose implications have not been fully appreciated. Here I examine some key findings on the extent of horizontal gene transfer (HGT) revealed by comparative genome analysis and their theoretical implications. In theoretical terms, HGT affects ideas pertaining to the tree of life, the notion of a last universal common ancestor, and the biological unities, as well as the rules of taxonomic nomenclature. This review discusses the emergence of the eukaryotic cell and the occurrence of HGT among metazoan phyla involving both transposable elements and structural genes for normal housekeeping functions. I also discuss the bacterial pangenome, which provides an important case study on the permeability of species boundaries. An interesting observation about bdelloid rotifers and their reversion to asexual reproduction as it pertains to HGT is included.",
author = "Michael Syvanen",
year = "2012",
doi = "10.1146/annurev-genet-110711-155529",
language = "English (US)",
volume = "46",
pages = "341--358",
journal = "Annual Review of Genetics",
issn = "0066-4197",
publisher = "Annual Reviews Inc.",

}

TY - JOUR

T1 - Evolutionary implications of horizontal gene transfer

AU - Syvanen, Michael

PY - 2012

Y1 - 2012

N2 - The flow of genes between different species represents a form of genetic variation whose implications have not been fully appreciated. Here I examine some key findings on the extent of horizontal gene transfer (HGT) revealed by comparative genome analysis and their theoretical implications. In theoretical terms, HGT affects ideas pertaining to the tree of life, the notion of a last universal common ancestor, and the biological unities, as well as the rules of taxonomic nomenclature. This review discusses the emergence of the eukaryotic cell and the occurrence of HGT among metazoan phyla involving both transposable elements and structural genes for normal housekeeping functions. I also discuss the bacterial pangenome, which provides an important case study on the permeability of species boundaries. An interesting observation about bdelloid rotifers and their reversion to asexual reproduction as it pertains to HGT is included.

AB - The flow of genes between different species represents a form of genetic variation whose implications have not been fully appreciated. Here I examine some key findings on the extent of horizontal gene transfer (HGT) revealed by comparative genome analysis and their theoretical implications. In theoretical terms, HGT affects ideas pertaining to the tree of life, the notion of a last universal common ancestor, and the biological unities, as well as the rules of taxonomic nomenclature. This review discusses the emergence of the eukaryotic cell and the occurrence of HGT among metazoan phyla involving both transposable elements and structural genes for normal housekeeping functions. I also discuss the bacterial pangenome, which provides an important case study on the permeability of species boundaries. An interesting observation about bdelloid rotifers and their reversion to asexual reproduction as it pertains to HGT is included.

UR - http://www.scopus.com/inward/record.url?scp=84870200615&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870200615&partnerID=8YFLogxK

U2 - 10.1146/annurev-genet-110711-155529

DO - 10.1146/annurev-genet-110711-155529

M3 - Article

VL - 46

SP - 341

EP - 358

JO - Annual Review of Genetics

JF - Annual Review of Genetics

SN - 0066-4197

ER -