Evidence for age-associated cognitive decline from Internet game scores

Jason Geyer; Philip Insel; Faraz Farzin; Daniel Sternberg; Joseph L. Hardy; Michael Scanlon; Dan M Mungas; Joel Kramer; R. Scott Mackin; Michael W. Weiner

doi:10.1016/j.dadm.2015.04.002

Evidence for age-associated cognitive decline from Internet game scores

Jason Geyer, Philip Insel, Faraz Farzin, Daniel Sternberg, Joseph L. Hardy, Michael Scanlon, Dan M Mungas, Joel Kramer, R. Scott Mackin, Michael W. Weiner

Neurology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Introduction: Lumosity's Memory Match (LMM) is an online game requiring visual working memory. Change in LMM scores may be associated with individual differences in age-related changes in working memory. Methods: Effects of age and time on LMM learning and forgetting rates were estimated using data from 1890 game sessions for users aged 40 to 79 years. Results: There were significant effects of age on baseline LMM scores (β=-.31, standard error or SE=.02, P<.0001) and lower learning rates (β=-.0066, SE=.0008, P<.0001). A sample size of 202 subjects/arm was estimated for a 1-year study for subjects in the lower quartile of game performance. Discussion: Online memory games have the potential to identify age-related decline in cognition and to identify subjects at risk for cognitive decline with smaller sample sizes and lower cost than traditional recruitment methods.

Original language	English (US)
Pages (from-to)	260-267
Number of pages	8
Journal	Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/j.dadm.2015.04.002
State	Published - 2015

Keywords

Alzheimer's disease
Cognitive decline
Internet game
Internet registry
Memory
Online cognitive assessments
Online games

ASJC Scopus subject areas

Psychiatry and Mental health
Clinical Neurology

Access to Document

10.1016/j.dadm.2015.04.002

Cite this

Evidence for age-associated cognitive decline from Internet game scores. / Geyer, Jason; Insel, Philip; Farzin, Faraz; Sternberg, Daniel; Hardy, Joseph L.; Scanlon, Michael; Mungas, Dan M; Kramer, Joel; Mackin, R. Scott; Weiner, Michael W.

In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, Vol. 1, No. 2, 2015, p. 260-267.

Research output: Contribution to journal › Article › peer-review

@article{6fae071f9d024cbba2d169d93c9d847c,

title = "Evidence for age-associated cognitive decline from Internet game scores",

abstract = "Introduction: Lumosity's Memory Match (LMM) is an online game requiring visual working memory. Change in LMM scores may be associated with individual differences in age-related changes in working memory. Methods: Effects of age and time on LMM learning and forgetting rates were estimated using data from 1890 game sessions for users aged 40 to 79 years. Results: There were significant effects of age on baseline LMM scores (β=-.31, standard error or SE=.02, P<.0001) and lower learning rates (β=-.0066, SE=.0008, P<.0001). A sample size of 202 subjects/arm was estimated for a 1-year study for subjects in the lower quartile of game performance. Discussion: Online memory games have the potential to identify age-related decline in cognition and to identify subjects at risk for cognitive decline with smaller sample sizes and lower cost than traditional recruitment methods.",

keywords = "Alzheimer's disease, Cognitive decline, Internet game, Internet registry, Memory, Online cognitive assessments, Online games",

author = "Jason Geyer and Philip Insel and Faraz Farzin and Daniel Sternberg and Hardy, {Joseph L.} and Michael Scanlon and Mungas, {Dan M} and Joel Kramer and Mackin, {R. Scott} and Weiner, {Michael W.}",

year = "2015",

doi = "10.1016/j.dadm.2015.04.002",

language = "English (US)",

volume = "1",

pages = "260--267",

journal = "Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring",

issn = "2352-8729",

publisher = "Elsevier BV",

number = "2",

}

TY - JOUR

T1 - Evidence for age-associated cognitive decline from Internet game scores

AU - Geyer, Jason

AU - Insel, Philip

AU - Farzin, Faraz

AU - Sternberg, Daniel

AU - Hardy, Joseph L.

AU - Scanlon, Michael

AU - Mungas, Dan M

AU - Kramer, Joel

AU - Mackin, R. Scott

AU - Weiner, Michael W.

PY - 2015

Y1 - 2015

N2 - Introduction: Lumosity's Memory Match (LMM) is an online game requiring visual working memory. Change in LMM scores may be associated with individual differences in age-related changes in working memory. Methods: Effects of age and time on LMM learning and forgetting rates were estimated using data from 1890 game sessions for users aged 40 to 79 years. Results: There were significant effects of age on baseline LMM scores (β=-.31, standard error or SE=.02, P<.0001) and lower learning rates (β=-.0066, SE=.0008, P<.0001). A sample size of 202 subjects/arm was estimated for a 1-year study for subjects in the lower quartile of game performance. Discussion: Online memory games have the potential to identify age-related decline in cognition and to identify subjects at risk for cognitive decline with smaller sample sizes and lower cost than traditional recruitment methods.

AB - Introduction: Lumosity's Memory Match (LMM) is an online game requiring visual working memory. Change in LMM scores may be associated with individual differences in age-related changes in working memory. Methods: Effects of age and time on LMM learning and forgetting rates were estimated using data from 1890 game sessions for users aged 40 to 79 years. Results: There were significant effects of age on baseline LMM scores (β=-.31, standard error or SE=.02, P<.0001) and lower learning rates (β=-.0066, SE=.0008, P<.0001). A sample size of 202 subjects/arm was estimated for a 1-year study for subjects in the lower quartile of game performance. Discussion: Online memory games have the potential to identify age-related decline in cognition and to identify subjects at risk for cognitive decline with smaller sample sizes and lower cost than traditional recruitment methods.

KW - Alzheimer's disease

KW - Cognitive decline

KW - Internet game

KW - Internet registry

KW - Memory

KW - Online cognitive assessments

KW - Online games

UR - http://www.scopus.com/inward/record.url?scp=84938695244&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938695244&partnerID=8YFLogxK

U2 - 10.1016/j.dadm.2015.04.002

DO - 10.1016/j.dadm.2015.04.002

M3 - Article

AN - SCOPUS:84938695244

VL - 1

SP - 260

EP - 267

JO - Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

JF - Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

SN - 2352-8729

IS - 2

ER -

Evidence for age-associated cognitive decline from Internet game scores

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this