Everyday cognition in older adults: Associations with neuropsychological performance and structural brain imaging

Sarah E Tomaszewski Farias, Lovingly Quitania Park, Danielle J Harvey, Christa Simon, Bruce R Reed, Owen Carmichael, Dan M Mungas

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Abstract The recently developed Everyday Cognition scales (ECog) measure multiple cognitively relevant functional domains (e.g., Everyday Memory, Everyday Language, Everyday Visuospatial abilities, and three everyday executive domains). The present study further evaluated the validity of the ECog by examining its relationship with objective measures of neuropsychological function, and neurobiological markers of disease as reflected by structural neuroimaging. Participants included 474 older adults (244 normals, 142 with MCI, 88 with dementia). The neuropsychological domains measured were episodic memory, semantic memory, spatial ability, and executive functioning. Brain MRI volumes included total brain (BV), hippocampus (HC) and dorsolateral prefrontal cortex (DLPFC). Neuropsychological measures of episodic memory and executive function were most consistently related to the ECog domains; spatial abilities had a specific relationship to the Everyday Visuospatial ECog domain. HC and BV volumes were related to most ECog domains, while DLPFC volume was independently related to two everyday executive domains (Everyday Planning and Everyday Organization). The pattern of associations varied somewhat as a function of diagnosis. Episodic memory and HC had more consistent associations with the ECog domains in older adults with MCI/dementia than in cognitively normal elderly. (JINS, 2013, 19, 1-12)

Original languageEnglish (US)
Pages (from-to)430-441
Number of pages12
JournalJournal of the International Neuropsychological Society
Volume19
Issue number4
DOIs
StatePublished - Apr 2013

Fingerprint

Neuroimaging
Cognition
cognition
brain
Episodic Memory
performance
Hippocampus
Prefrontal Cortex
dementia
Dementia
ability
Aptitude
colloquial
Executive Function
Brain
Semantics
Brain Imaging
Language
semantics
Disease

Keywords

  • Activities of daily living
  • Dementia
  • Episodic memory
  • Executive function
  • Functional abilities
  • Instrumental activities of daily living
  • MCI
  • Neuroimaging

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Clinical Psychology
  • Neuroscience(all)
  • Language and Linguistics
  • Linguistics and Language

Cite this

@article{e7d99ef8b4054cf3904c2077c52652ca,
title = "Everyday cognition in older adults: Associations with neuropsychological performance and structural brain imaging",
abstract = "Abstract The recently developed Everyday Cognition scales (ECog) measure multiple cognitively relevant functional domains (e.g., Everyday Memory, Everyday Language, Everyday Visuospatial abilities, and three everyday executive domains). The present study further evaluated the validity of the ECog by examining its relationship with objective measures of neuropsychological function, and neurobiological markers of disease as reflected by structural neuroimaging. Participants included 474 older adults (244 normals, 142 with MCI, 88 with dementia). The neuropsychological domains measured were episodic memory, semantic memory, spatial ability, and executive functioning. Brain MRI volumes included total brain (BV), hippocampus (HC) and dorsolateral prefrontal cortex (DLPFC). Neuropsychological measures of episodic memory and executive function were most consistently related to the ECog domains; spatial abilities had a specific relationship to the Everyday Visuospatial ECog domain. HC and BV volumes were related to most ECog domains, while DLPFC volume was independently related to two everyday executive domains (Everyday Planning and Everyday Organization). The pattern of associations varied somewhat as a function of diagnosis. Episodic memory and HC had more consistent associations with the ECog domains in older adults with MCI/dementia than in cognitively normal elderly. (JINS, 2013, 19, 1-12)",
keywords = "Activities of daily living, Dementia, Episodic memory, Executive function, Functional abilities, Instrumental activities of daily living, MCI, Neuroimaging",
author = "{Tomaszewski Farias}, {Sarah E} and Park, {Lovingly Quitania} and Harvey, {Danielle J} and Christa Simon and Reed, {Bruce R} and Owen Carmichael and Mungas, {Dan M}",
year = "2013",
month = "4",
doi = "10.1017/S1355617712001609",
language = "English (US)",
volume = "19",
pages = "430--441",
journal = "Journal of the International Neuropsychological Society",
issn = "1355-6177",
publisher = "Cambridge University Press",
number = "4",

}

TY - JOUR

T1 - Everyday cognition in older adults

T2 - Associations with neuropsychological performance and structural brain imaging

AU - Tomaszewski Farias, Sarah E

AU - Park, Lovingly Quitania

AU - Harvey, Danielle J

AU - Simon, Christa

AU - Reed, Bruce R

AU - Carmichael, Owen

AU - Mungas, Dan M

PY - 2013/4

Y1 - 2013/4

N2 - Abstract The recently developed Everyday Cognition scales (ECog) measure multiple cognitively relevant functional domains (e.g., Everyday Memory, Everyday Language, Everyday Visuospatial abilities, and three everyday executive domains). The present study further evaluated the validity of the ECog by examining its relationship with objective measures of neuropsychological function, and neurobiological markers of disease as reflected by structural neuroimaging. Participants included 474 older adults (244 normals, 142 with MCI, 88 with dementia). The neuropsychological domains measured were episodic memory, semantic memory, spatial ability, and executive functioning. Brain MRI volumes included total brain (BV), hippocampus (HC) and dorsolateral prefrontal cortex (DLPFC). Neuropsychological measures of episodic memory and executive function were most consistently related to the ECog domains; spatial abilities had a specific relationship to the Everyday Visuospatial ECog domain. HC and BV volumes were related to most ECog domains, while DLPFC volume was independently related to two everyday executive domains (Everyday Planning and Everyday Organization). The pattern of associations varied somewhat as a function of diagnosis. Episodic memory and HC had more consistent associations with the ECog domains in older adults with MCI/dementia than in cognitively normal elderly. (JINS, 2013, 19, 1-12)

AB - Abstract The recently developed Everyday Cognition scales (ECog) measure multiple cognitively relevant functional domains (e.g., Everyday Memory, Everyday Language, Everyday Visuospatial abilities, and three everyday executive domains). The present study further evaluated the validity of the ECog by examining its relationship with objective measures of neuropsychological function, and neurobiological markers of disease as reflected by structural neuroimaging. Participants included 474 older adults (244 normals, 142 with MCI, 88 with dementia). The neuropsychological domains measured were episodic memory, semantic memory, spatial ability, and executive functioning. Brain MRI volumes included total brain (BV), hippocampus (HC) and dorsolateral prefrontal cortex (DLPFC). Neuropsychological measures of episodic memory and executive function were most consistently related to the ECog domains; spatial abilities had a specific relationship to the Everyday Visuospatial ECog domain. HC and BV volumes were related to most ECog domains, while DLPFC volume was independently related to two everyday executive domains (Everyday Planning and Everyday Organization). The pattern of associations varied somewhat as a function of diagnosis. Episodic memory and HC had more consistent associations with the ECog domains in older adults with MCI/dementia than in cognitively normal elderly. (JINS, 2013, 19, 1-12)

KW - Activities of daily living

KW - Dementia

KW - Episodic memory

KW - Executive function

KW - Functional abilities

KW - Instrumental activities of daily living

KW - MCI

KW - Neuroimaging

UR - http://www.scopus.com/inward/record.url?scp=84876742515&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876742515&partnerID=8YFLogxK

U2 - 10.1017/S1355617712001609

DO - 10.1017/S1355617712001609

M3 - Article

C2 - 23369894

AN - SCOPUS:84876742515

VL - 19

SP - 430

EP - 441

JO - Journal of the International Neuropsychological Society

JF - Journal of the International Neuropsychological Society

SN - 1355-6177

IS - 4

ER -