Everyday cognition in older adults: Associations with neuropsychological performance and structural brain imaging

Sarah E Tomaszewski Farias, Lovingly Quitania Park, Danielle J Harvey, Christa Simon, Bruce R Reed, Owen Carmichael, Dan M Mungas

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


Abstract The recently developed Everyday Cognition scales (ECog) measure multiple cognitively relevant functional domains (e.g., Everyday Memory, Everyday Language, Everyday Visuospatial abilities, and three everyday executive domains). The present study further evaluated the validity of the ECog by examining its relationship with objective measures of neuropsychological function, and neurobiological markers of disease as reflected by structural neuroimaging. Participants included 474 older adults (244 normals, 142 with MCI, 88 with dementia). The neuropsychological domains measured were episodic memory, semantic memory, spatial ability, and executive functioning. Brain MRI volumes included total brain (BV), hippocampus (HC) and dorsolateral prefrontal cortex (DLPFC). Neuropsychological measures of episodic memory and executive function were most consistently related to the ECog domains; spatial abilities had a specific relationship to the Everyday Visuospatial ECog domain. HC and BV volumes were related to most ECog domains, while DLPFC volume was independently related to two everyday executive domains (Everyday Planning and Everyday Organization). The pattern of associations varied somewhat as a function of diagnosis. Episodic memory and HC had more consistent associations with the ECog domains in older adults with MCI/dementia than in cognitively normal elderly. (JINS, 2013, 19, 1-12)

Original languageEnglish (US)
Pages (from-to)430-441
Number of pages12
JournalJournal of the International Neuropsychological Society
Issue number4
StatePublished - Apr 2013


  • Activities of daily living
  • Dementia
  • Episodic memory
  • Executive function
  • Functional abilities
  • Instrumental activities of daily living
  • MCI
  • Neuroimaging

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Clinical Psychology
  • Neuroscience(all)
  • Language and Linguistics
  • Linguistics and Language


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